Effects of different anesthesia methods on early neurological prognosis of patients with acute basilar artery occlusion treated by endovascular therapy

DU Haibin; TONG Xu; ZHANG Dong; SUN Jian

doi:10.3969/j.issn.1004-3594.2026.05.002

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Medical Journal of the Chinese People Armed Police Forces ›› 2026, Vol. 37 ›› Issue (5) : 376-381. DOI: 10.3969/j.issn.1004-3594.2026.05.002

ORIGINAL ARTICLES

Effects of different anesthesia methods on early neurological prognosis of patients with acute basilar artery occlusion treated by endovascular therapy

DU Haibin¹, TONG Xu², ZHANG Dong³, SUN Jian¹

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Abstract

Objective To investigate the effects of general anesthesia and conscious sedation anesthesia on the early neurological prognosis of patients with acute basilar artery occlusion (BAO) treated by endovascular therapy. Methods The clinical data of 178 patients with acute BAO who received endovascular therapy in Beijing Tiantan Hospital from May 2018 to April 2024 were retrospectively analyzed. The patients were divided into a general anesthesia group (n=139) and a conscious sedation anesthesia group (n=39). National Institutes of Health Stroke Scale (NIHSS) scores of the two groups were recorded before and 24 hours after surgery. Univariate analysis was performed to screen variables, followed by multivariable logistic regression to explore the effects of different anesthesia methods on the early neurological function of the patients. Results There was no statistically significant difference between the two groups in age, gender, cerebrovascular high-risk factors, onset mode, preoperative laboratory tests, occlusion site, and stroke type. Compared with the conscious sedation anesthesia group, the preoperative NIHSS score of the general anesthesia group [22 (11,35) vs. 16 (6,30)] and the postoperative 24-hour NIHSS score [17 (16,20) vs. 9(8,14)] were higher, the intraoperative stent thrombectomy rate, the intra-arterial tirofiban use rate and intraoperative angioplasty operation rate were higher, and the duration of anesthesia was longer, and all differences were statistically significant (P<0.05). Multivariate analysis showed that there was a statistically significant difference in early neurological improvement between the two groups (OR=0.31; 95%CI: 0.11-0.84; P=0.02). Conclusions Anesthesia method is an independent factor influencing the early neurological prognosis of patients with acute BAO treated by endovascular therapy, and general anesthesia is associated with poorer early neurological prognosis.

Key words

anesthesia / basilar artery occlusion / endovascular therapy / early neurological function / prognosis

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DU Haibin, TONG Xu, ZHANG Dong, SUN Jian. Effects of different anesthesia methods on early neurological prognosis of patients with acute basilar artery occlusion treated by endovascular therapy[J]. Medical Journal of the Chinese People Armed Police Forces. 2026, 37(5): 376-381 https://doi.org/10.3969/j.issn.1004-3594.2026.05.002

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