Objective To evaluate the efficacy and safety of a novel CT-guided memory alloy puncture localization needle (with a spring-coil tip at the front end) in thoracoscopic resection of pulmonary nodules. Methods A retrospective analysis was conducted on 40 patients who underwent thoracoscopic pulmonary nodule resection between June 2023 and January 2025. Ten patients received CT-guided localization using a new needle before the operation (localization-assisted group), while 30 patients underwent conventional thoracoscopic surgery (conventional surgery group). Localization success rate, operative time, intraoperative blood loss, hospital stay, and complication rates were recorded and compared between the two groups. Results The localization technique and nodule resection success rates of the 10 patients were both 100% in the localization-assisted group (10 patients). Compared with the conventional surgery group, the localization-assisted group demonstrated significantly shorter operative time and significantly reduced intraoperative blood loss (all P<0.05). The complication rate was lower in the localization-assisted group (1 case of mild pneumothorax/subcutaneous emphysema; 1 case of transient intraoperative pain). There was no statistically significant difference in hospital stay between the two groups (P=0.201). Conclusions The novel CT-guided memory alloy puncture localization needle is safe and effective for thoracoscopic pulmonary nodule resection. It is precise and reliable in localization, can significantly shorten the operative time, reduce intraoperative bleeding, and has fewer complications.

Objective To investigate the therapeutic efficacy of a compound traditional Chinese medicine decoction combined with electroacupuncture in a rat model of non-alcoholic fatty liver disease(NAFLD). Methods An NAFLD rat model was established through high-fat diet(HFD) feeding plus intraperitoneal injection of carbon tetrachloride(CCl4) corn oil mixture. After 8 weeks of modeling, successfully modeled rats were randomized into five groups(n=10): HFD group, normal diet(ND) group, electroacupuncture(EA) group, compound traditional Chinese medicine decoction(TCM) group, and combined therapy(EA-TCM) group. The HFD group received continuous HFD feeding; the ND group switched to normal diet; the EA group underwent electroacupuncture at bilateral “Zusanli”(ST 36), “Fenglong”(ST 40), “Sanyinjiao”(SP 6), “Taichong”(LR 3) and a non-acupoint on the tail, once daily for 5 days per week; the TCM group received intragastric administration of compound traditional Chinese medicine decoction at 1 ml/100 g twice daily; the EA-TCM group received both electroacupuncture and decoction for 4 consecutive weeks. Liver histopathology was observed through HE staining. Serum indicators including liver function, blood lipids, oxidative stress, glucose metabolism and renal function were measured. Results Compared with the HFD group, all treatment groups showed reduced hepatic steatosis and ballooning degeneration, with the combined therapy group demonstrating the most pronounced improvement. For blood lipids, the EA-TCM group exhibited significantly decreased TC, TG and LDL-C levels and elevated HDL-C(P<0.05), while the EA and TCM groups showed comparable effects. Regarding liver function, the EA-TCM group displayed markedly reduced ALT and AST activities(P<0.05). In terms of oxidative stress, the EA-TCM group had significantly increased T-SOD activity and decreased MDA content(P<0.05). For glucose metabolism, the EA, TCM and EA-TCM groups all showed significantly lowered GLU levels(P<0.05), whereas no significant differences emerged in GSP across groups. Safety assessment revealed no significant differences in renal function indicators BUN and CREA among all groups. Conclusion Both the compound traditional Chinese medicine decoction and electroacupuncture confer measurable therapeutic benefit against NAFLD in rats, with their combined application yielding superior efficacy.

Objective To analyze the MRI-based assessment of the correlation between glenohumeral joint anatomy and Bankart lesion in males. Methods A total of 120 patients diagnosed with Bankart lesion at Zhejiang Provincial Corps Hospital of Chinese People's Armed Police Force from May 2021 to May 2025 were selected as the study group. Through the medical imaging management system (PACS) and electronic medical record system, another 120 patients who visited the hospital due to shoulder joint discomfort during the same period were selected as the control group, excluding those with previous shoulder joint dislocation, surgery, or trauma history. Both groups underwent MRI examination. The MRI imaging features of Bankart lesions were observed and analyzed. The width and height of glenoid, the width and height of humeral head, the ratio of the width and height of glenoid, and the rate of glenohumeral dislocation were measured and compared between the two groups. Logistic regression analysis was used to evaluate the high-risk factors of Bankart lesion of the shoulder joint, and the receiver operating characteristic (ROC) curve was used to assess the predictive value of related indicators. Results Bankart lesions showed irregular, blunt or missing labrum morphology on MRI images, T2WI showed high signal intensity in labrum and glenoid articular surface separation, accompanied by Hill-Sachs fracture of the humeral head. There was no statistically significant difference in the height and width of the glenoid fossa and humeral head width between the two groups (P＞0.05), The width and surface area of the glenoid of the study group were smaller than those of the control group, while the ratio of the height to width of the glenoid and the rate of glenohumeral mismatch were greater than those of the control group, with statistically significant differences (P<0.05). Age, BMI index, glenoid height and humeral head width were not risk factors for Bankart lesion of the shoulder joint, while the glenoid width, the ratio of glenoid height to width and the rate of glenohumeral dislocation were risk factors (P<0.05). Glenoid height-to-width ratio (OR=243.69,95%CI:13.17~4508.72) was an independent risk factor for Bankart lesion. The area under the curve (AUC) of glenoid height-to-width ratio predicting Bankart lesion was 0.72, with an optimal cut-off value of 1.60, sensitivity of 71.67%, and specificity of 54.17%. Conclusions MRI can accurately display glenoid labrum lesion of shoulder joint and is a reliable method to diagnose the lesion. A larger glenoid height-to-width ratio is an important risk factor for anterior instability of shoulder joint in males.

Objective To explore the significance of immune function indicators in the clinical examination of children with neuroblastoma (NB). Methods The clinical data of 393 pediatric patients with NB (199 males, 194 females) treated at Beijing Children's Hospital Affiliated to Capital Medical University from 2018 to 2023 were retrospectively analyzed, while 67 normal healthy children (38 males, 29 females)who underwent physical examinations during the same period were selected as the control group. At initial evaluation, serum immunoglobulins (IgG, IgA, IgM) and total IgE were compared between the two groups. Through cellular immunity in blood and flow cytometry, the levels of peripheral blood T lymphocytes (CD3⁺, CD4⁺, CD8⁺, CD4⁺/CD8⁺), B cells (CD19⁺), and natural killer (NK) cells (CD16⁺CD56⁺) were detected. Results NB predominantly affected children aged 0-3 years (n=208 in this cohort). Compared with healthy controls, children with NB had significantly lower levels of CD3⁺, CD4⁺, and CD4⁺/CD8⁺, and significantly higher levels of CD8⁺ and NK cells, with statistically significant differences between the two groups (P<0.05). No significant difference was observed in the level of B cells (Z=-1.909, P=0.056). The levels of IgG, IgA, and IgE were significantly higher in the NB group than i those in the control group, and the differences were statistically significant(P<0.05), whereas the level of IgM showed no significant difference. Conclusions Pediatric NB is associated with dysregulation of both cellular and humoral immunity. Monitoring the levels of lymphocyte subsets and Ig series in children may facilitate the evaluation of the cellular and humoral immune functions of the affected children.

Objective To investigate the current status of cardiovascular health in patients with chronic kidney disease(CKD) and analyze the influencing factors in order to provide references for improving the cardiovascular health of CKD patients. Methods Through the convenient sampling method, 220 patients who visited the nephrology department of a tertiary hospital in Beijing from April to June 2023 were selected. General information questionnaire, the scale of cardiovascular health knowledge for CKD patients, chronic disease self-efficacy scale, positive and negative affective scales and cardiovascular health assessment tools were used for investigation. Univariate analysis, correlation analysis and multiple linear stepwise regression analysis were used to analyze the influencing factors. Results A total of 217 valid questionnaires were collected, with a valid questionnaire recovery rate of 98.6%. The score of cardiovascular health in CKD patients was (61.69±12.10) points. Multiple linear stepwise regression analysis showed that waistline, 24 h urine protein quantification, blood urea, follow-up frequency, diabetes history, negative emotion and mastery of cardiovascular health knowledge were the influencing factors of cardiovascular health in CKD patients. Conclusions CKD patients with normal blood urea, 24 h urine protein quantification <1 g, no history of diabetes and follow-up visit frequency ≤6 months have better cardiovascular health, while the patients with thicker waistline, more negative emotions, and less knowledge of cardiovascular health have poorer cardiovascular health. It is recommended to customize personalized plans based on the cardiovascular health status of CKD patients and to conduct early intervention to improve prognosis.

Objective To analyze the multi-slice spiral CT (MSCT) imaging features of mediastinal bronchial cysts (MBC) to guide clinical diagnosis and differential diagnosis. Methods A retrospective analysis was conducted on the MSCT features of 31 cases of MBC with complete clinical data and confirmed by surgery and pathology. The location, morphology, density, margin, cyst wall, degree of enhancement, etc. of the lesions in the mediastinum were observed and classified, and compared with previous literatures. Results For the first time, it was found that the anterior mediastinum was a new predominant distribution area of MBC (13/31, 41.9%), and the location was significantly correlated with the density (P=0.032), with a low-density proportion of 53.8% (OR=4.08). Three-dimensional morphological analysis showed that 96.8% (30/31) of the cases had a characteristic “ellipsoid-like” morphology, and 48.4% (15/31) of the cases showed a “ellipsoid-like - parallel vascular sign” composite sign, with the long axis consistent with the course of adjacent vessels. There was no enhancement on enhanced scanning. Conclusions The combination of features such as anatomical-density association, ellipsoid morphological index and parallel vascular sign can improve the diagnostic accuracy of MBC.

Objective To investigate the value of the MRI-based radiomics model in predicting the recurrence of non-enhancing diffuse gliomas within 5 years after surgery. Methods A retrospective analysis was conducted on 116 patients with pathologically confirmed non-enhanced diffuse gliomas treated at Beijing Tiantan Hospital Affiliated to Capital Medical University from June 2016 to June 2020. Clinical pathological data, MRI images, and follow-up information were collected. Radiomics features and tumor location features were extracted using Python pyradiomics and Atlasquery tools. The LASSO algorithm was applied for feature dimensionality reduction and selection. Five predictive models were constructed as follows: Model-1 (Sex and Age), Model-2 (Tumor Location), Model-3 (Radiomics), Model-4 (Tumor Location + Radiomics), and Model-5 (Sex+Age+Tumor Location+Radiomics). Receiver operating characteristic (ROC) curves and decision curve analysis (DCA) were plotted to evaluate the predictive performance of the models. Results The areas under the ROC curve (AUC) for predicting postoperative recurrence were 0.529 (Model-1), 0.680 (Model-2), 0.912 (Model-3), 0.911 (Model -4), and 0.917 (Model-5), respectively. Model-5 demonstrated the best performance, achieving a sensitivity of 0.837, specificity of 0.866, and accuracy of 0.863, respectively in the test set. Conclusions The MRI radiomics-based model has high clinical value in predicting recurrence of non-enhancing diffuse gliomas within 5 years after surgery.

Objective To investigate the effect of the ISBAR-CICARE communication mode on clinical outcomes in patients with lumbar disc herniation(LDH) undergoing three-dimensional balanced chiropractic treatment. Methods A total of 144 patients with lumbar disc herniation(LDH) who underwent three-dimensional balanced chiropractic treatment at the Affiliated, Shoulder, lumbar, and Leg Pain Hospital of to Shandong First Medical University from October 2024 to December 2025 were enrolled. Using a random number table method, they were divided into an observation group(ISBAR-CICARE communication mode group) and a control group(conventional communication group), with 72 patients in each group. Both groups received the same three-dimensional balanced chiropractic treatment. The control group adopted the department's routine health education and doctor-patient communication methods, without systematic application of a structured communication mode. Nurses in the observation group systematically applied the ISBAR-CICARE structured communication process before, during, and after treatment. Comparative analysis was conducted on the visual analog scale(VAS) pain scores, Hospital Anxiety and Depression Scale(HADS) scores, Japanese Orthopedic Association(JOA) assessment scores, and nursing satisfaction based on the Chinese version of the Nursing Presence Scale for Hospitalized Patieats (NPSHP) before and after intervention in both groups. Results No significant differences were found in baseline characteristics and outcome measures between the two groups before the intervention. After the intervention, the observation group demonstrated significantly lower scores than the control group on the VAS[(1.29±0.95) vs. (2.43±1.01)], HADS-Anxiety[(2.5±1.27) vs. (5.85±2.85)], and HADS-Depression[(1.5±0.93) vs. (3.56±1.63)](P<0.05). Furthermore, the observation group showed significantly greater improvement in JOA scores[(27.46±2.04) vs. (21.17±2.16),P<0.05]. The nursing satisfaction rate was significantly higher in the observation group than in the control group(94.44% vs. 79.17%, P<0.05). Conclusions Applying the ISBAR-CICARE communication mode to LDH patients undergoing three-dimensional balanced chiropractic treatment can enhance patient cooperation, relieve pain, reduce anxiety and depression, significantly improve service satisfaction, and promote the recovery of lumbar function. These findings support its broader implementation in clinical practice.

Objective To investigate the return to military training after anterior cruciate ligament reconstruction (ACLR) among the officers and soldiers in a military unit and its influencing factors. Methods A total of 160 officers and soldiers who underwent ACLR at a subordinate hospital of Chinese People's Armed Police Force from January 2020 to November 2023 were selected as the research subjects. Demographic characteristics, occupational information, and follow-up data 9 months after surgery were collected. The subjects were divided into groups based on whether they returned to military training 1 year after surgery, and the logistic regression method was used to analyze the influencing factors. Results Of the 160 cases, 103 (64.3%) returned to military training. The multivariate logistic regression analysis showed that occupational role (OR=16.094, 95% CI: 1.645-79.43), 3000 m running time/s, 30×2 agility running time/s, sleep quality, ACL-RSI score and Limb Symmetry Index (LSI) of the single leg hop 9 months after surgery were independent risk factors associated with their return to military training (all P<0.05). Conclusions Service members in command roles, better aerobic endurance and knee coordination, no sleep disorders, and higher ACL-RSI score and LSI index of the single leg hop 9 months after surgery are conducive to the return to military training for officers and soldiers.

Objective To explore the correlation between serum total bilirubin and coronary atherosclerotic lesions in patients with Type 2 diabetes (T2DM) complicated with metabolic dysfunction. Methods A retrospective study was conducted on the clinical data of patients with T2DM and metabolic dysfunction who were hospitalized in the First Hospital of Qinhuangdao from February 2016 to October 2023. According to coronary artery computed tomography angiography (CTA) results, the patients were grouped, and the gender, age, serum total bilirubin, and lipid indicators of the two groups were collected for comparison. The correlations between serum total bilirubin levels and plaque burden, involved segments, and plaque phenotypes was also explored. Results A total of 77 patients were included in this study. According to the CTA results, they were divided into a T2DM with the coronary heart disease (CHD) group (n=42) and a T2DM group (n=35).The serum total bilirubin level in the T2DM with CHD group was significantly lower than that in the T2DM group [9.40(7.25-12.53) vs. 10.50(6.65-13.95)μmol/L], and the difference was statistically significant (P<0.05). Compared with T2DM group, the serum total bilirubin levels in the T2DM+CHD group were significantly negatively correlated with plaque number and the number of involved segments (r=-0.82、-0.58,P<0.001), and also negatively correlated with calcification, non-calcification, and mixed plaques (r=-0.49, -0.57, -0.92, P<0.05). Conclusions Serum total bilirubin levels are significantly reduced in T2DM patients with CHD and are associated with higher coronary plaque burden and unstable plaque characteristics.