Objective To compare the hemodynamic response and ventilation after standard cardiopulmonary resuscitation (S-CPR) and cardiac massage under the diaphragmatic muscle (D-CPR)during laparotomy in cardiac arrest of swine. Methods Fourteen healthy domestic pigs were anesthetized and intubated. After preoperotive preparation and the hemodynamics was stable for 5 minutes, the readings of aortic systolic pressure(AOS), aortic diastolic pressure(AOD), and right atrial pressure(RAP) were recorded consecutively. Pigs were randomized to receive either S-CPR (n=7) or D-CPR (n=7). Cardiac arrest was induced with overdosed bupivacaine. After 2 min of untreated time, they were resuscitated, and hemodynamic variables, PETCO2, VT and ECG were continuously recorded. Coronary perfusion pressure (CPP) was calculated as arterial diastolic pressure minus right atrial diastolic pressure. Results D-CPR during cardiac massage, compared with S-CPR, resulted in a significant increase in VT, DAP and CPP. Conclusions D-CPR can provide higher arterial pressure and ventilation; D-CPR is superior to S-CPR.
Key words
cardiopulmonary resuscitation /
diaphragmatic muscle /
tidal volume /
coronary perfusion pressure
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References
[1] Field J M, Hazinski M F, Sayre M R, et al. Part 1. Executive summary: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care[J]. Circulation, 2010, 122(18): 640-656.
[2] 王立祥, 沈中阳. 膈肌下抬挤心肺复苏法[J]. 中国危重病急救医学, 2010, 22(2): 71-72.
[3] 王立祥, 郑静晨. 单纯腹部提压: 一种心肺复苏的新方法[J]. 中国危重病急救医学, 2009, 21 (6): 323-324.
[4] 王立祥, 郑静晨, 侯世科, 等. 腹部提压心肺复苏新装置[J]. 武警医学, 2009, 20 (5): 455-456.
[5] Ahrens T, Schallom L, Bettorf K, et al. End-tidal carbon dioxide measurements as a prognostic indicator of outcome in cardiac arrest[J]. Am J Crit Care,2001, 10(6): 391-398.
[6] Kolar M, Krizmaric M, Klemen P, et al. Partial pressure of end-tidal carbon dioxide successful predicts cardiopulmonary resuscitation in the field: a prospective observational study[J]. Crit Care, 2008, 12(5): R115.
[7] Thomas N J. Effective coronary perfusion pressure[J]. Am Heart J, 1961, 62(9): 427-429.
[8] Joshua C, Reynolds M D, David D, et al. Coronary perfusion pressure and return of spontaneous circulation after prolonged cardiac arrest[C]. The American Heart Association Resuscitation Science Symposium, New Orleans, Louisiana, November 2008.
[9] Yu T, Weil M H, Tang W, et al. Adverse out-comes of interrupted precordial compression during automated defibrillation[J]. Circulation, 2002, 106(3): 368-372.
[10] 王立祥, 陈新国, 李 威, 等. 经膈肌下抬挤心脏急救肝移植术中心搏骤停[J].中华急诊医学杂志, 2008, 17(12): 1314-1315.[ZK)]
(2012-06-17