Objective To analyze the characteristics of disease spectrum during floods in Pakistan in order to provide a scientific basis for skin disease control and prevention in the future. Methods The data of 1326 patients with skin disease at the temporary outpatient clinic of the Chinese rescue team were statistically analyzed. Results There were many kinds of skin diseases after floods. The most prevalent skin problem was allergic skin diseases (548 cases, 41.3%), followed by bacterial infections (388 cases, 29.3%) , and fungal infections (202 cases, 15.2%). The top three in skin disease spectrum were pruritus (228 cases, 17.2%) ，impetigo (214 cases, 16.1%) and eczema (205 cases, 15.5%). Conclusions The incidence of skin diseases, allergic and infectious skin diseases in particular, is high among the refugees in Pakistan after floods. Preventive and remedial measures are required according to the characteristics of the disease spectrum．