Serum NGAL level and severity of illness in patients with acute renal failure

MA Yuguo; ZHAO Hongli; QIAO Shunyi; ZHANG Yanli; and ZHAO Erqiang

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Medical Journal of the Chinese People Armed Police Forces ›› 2012, Vol. 23 ›› Issue (7) : 563-564.

Serum NGAL level and severity of illness in patients with acute renal failure

MA Yuguo,ZHAO Hongli,QIAO Shunyi,ZHANG Yanli,and ZHAO Erqiang,

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Abstract

Objective To investigate the relationship of serum NGAL level and severity of illness in patients with acute renal failure(ARF). Methods Serum NGAL was detected using ELISA while the severity of illness of all ARF patients were evaluated by APACHE Ⅲ score system. Results Serum NGAL level in ARF patients was markedly higher than that in the control group and positively correlated with APACHE Ⅲ scores. Conclusions Serum NGAL level may be one biomarker for severity of illness in ARF patients and real time monitoring of serum NGAL level in ARF patients may shorten the evaluation time for severity of illness.

Key words

acute renal failure / neutrophil gelatinase-associated lipocalin / acute physiology and chronic health evaluation Ⅲ

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MA Yuguo,ZHAO Hongli,QIAO Shunyi,ZHANG Yanli,and ZHAO Erqiang. Serum NGAL level and severity of illness in patients with acute renal failure[J]. Medical Journal of the Chinese People Armed Police Forces. 2012, 23(7): 563-564

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