Changes in p-selection and glycoprotein Ⅱb/Ⅲa on the surface of platelets between healthy individuals and elderly patients with coronary heart disease(CHD)

XIONG Zhijian,LI Dandan,LI Hong,ZOU Hui,ZHANG Liping,and DU Xunhui.

Medical Journal of the Chinese People Armed Police Forces ›› 2012, Vol. 23 ›› Issue (9) : 763-766.

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PDF(785 KB)
Medical Journal of the Chinese People Armed Police Forces ›› 2012, Vol. 23 ›› Issue (9) : 763-766.

Changes in p-selection and glycoprotein Ⅱb/Ⅲa on the surface of platelets between healthy individuals and elderly patients with coronary heart disease(CHD)

  • XIONG Zhijian1,LI Dandan1,LI Hong2,ZOU Hui1,ZHANG Liping1,and DU Xunhui1.
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Abstract

Objective To investigate the changes in tyrosine phosphatase(CD148),P-selection (CD62P) and glyco1protein Ⅱb/Ⅲa(PAC-1) in platelets of elderly patients with coronary heart disease(CHD).Methods CD148,CD62P and PAC-1 in platelets were analyzed by flow cytometric 3-color immunofluorescence.Results The percentage and MFI of CD62 expression in the platelet membrane in elderly patients with coronary heart disease(CHD) were increased compared with healthy individuals(6.24 vs 0.89,P

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XIONG Zhijian,LI Dandan,LI Hong,ZOU Hui,ZHANG Liping,and DU Xunhui.. Changes in p-selection and glycoprotein Ⅱb/Ⅲa on the surface of platelets between healthy individuals and elderly patients with coronary heart disease(CHD)[J]. Medical Journal of the Chinese People Armed Police Forces. 2012, 23(9): 763-766

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