Objective To investigate the distribution of irregular red blood cell antibodies, the detection rate and the irregular antibody specificity among patients in Yangzhou area. Methods From January 2010 to December 2012, 18 625 patients in Armed Police Forces Jiangsu Corps Hospital or clinic patients were examined by antibody screening method, application of saline, antiglobulin method, polybrene method for detection of irregular antibodies, and the positive screening results against the identification of antibody specificity. Results Irregular antibody were identified in 136 cases, accounting for 0.73% of the total screened population, of whom 21 were male, 115 female. Irregular antibodies were autoantibodies in 45 cases and homospecific antibodies in 77 cases. Conclusion Patients with irregular antibodies have blood transfusion history and, for pregnant women, autoantibodies mainly occur in the elderly and in patients with autoimmune disease.
Key words
blood transfusion /
blood transfusion history /
pregnancy /
antibody screening /
irregular antibody
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References
[1] 李文静,蒋学兵,王燕菊,等.输血前不规则抗体筛查与临床输血安全[J].国际检验医学杂志,2012,33(17):2065-2068
[2] 吴远军,刘彦慧,刘兴玲,等.汉族患者(30800例)及孕妇(4200例)红细胞血型不规则抗体分布的调查[J].第四军医大学学报,2007,28(10):922-925.
[3] 柯秋高,彭秀春,杨毓明,等.2638名患者红细胞血型不规则抗体调查[J].中国输血杂志,2009,22(6):463-465.
[4] 向 东,张雄民,王健莲,等.220例患者血型不规则抗体分析[J].临床输血与检验,2003,5(2): 103-105.
[5] 邓梅英,陈 宇,王锦恒,等.6036例输血患者不规则抗体检测临床观察[J].重庆医学,2010,39(7):839-840.
[6] 王立萍,阎东河,赵月凯.多次输血、妊娠产生Rh血型抗体16例[J].中国输血杂志.2005,18(03):64-65.
[7] 蔡 葵,容伯芬.5840例输血患者的血型不规则抗体筛查[J].临床输血与检验.2009,11(02):83-84.
[8] 杨 珊.165例患者不规则抗体筛选结果分析及临床意义[J].检验医学与临床.2010,7(17):78-79.
[9] 王桂萍,罗小华.4680例患者不规则抗体筛查结果分析[J].川北医学院学报.2010,25(06):60-61.
[10] 陆紫敏,祖亚钧,梁 萍,等.输血与血型不规则抗体检测的关系[J].临床血液学杂志(输血与检验版).2009,6(06):5-7.
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