Objective To evaluate the application of echocardiography technology for the treatment of acute pulmonary embolism effect evaluation. Methods Between February 2009 and November 2013,from departments of respiratory medicine and cardiology in Armed Police hospital, 48 patients with acute pulmonary embolism were recruited. In thrombolysis and anticoagulation therapy before and after treatment for 3 months,6 months and 12 months, echocardiography was conducted. Measure indicators including right ventricular diameter (RVD),left ventricular diameter(LVD),right atrial diameter (RAD), left atrial diameter (LAD),main pulmonary artery diameter (MPAD), pressure gradient of tricuspid valve regurgitation(PGTR), right ventricular anterior wall motion(RVAWM), RVD/LVD、RAD/LAD and SPAP, were calculated. Results SPAP with RA/LA improvement was most obvious when anticoagulation in March . As time went on, change was not obvious. After anticoagulant treatment for 3 month and 6 month, the RV/LV obviously improved,there were still changes after treatment for 12 months.MPAD and EF had no changes before and after treatment and follow-up. After follow-up of all 48 patients for 12 months, 4 patients had chronic thromboembolic pulmonary hypertension. Conclusions Echocardiogaphy can be used as a practical technology for noninvasive evaluation of curative effect on acute pulmonary embolism.