Relationship between olfactory dysfunction and eosinophil counts in eosinophilic chronic sinusitis

ZHAO Songhua; SUN Shaohui; CHEN Na; ZHU Qi; CHEN Yu; SHE Wenyu; LIU Hui

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Medical Journal of the Chinese People Armed Police Forces ›› 2015, Vol. 26 ›› Issue (4) : 350-352.

ORIGINAL ARTICLES

Relationship between olfactory dysfunction and eosinophil counts in eosinophilic chronic sinusitis

ZHAO Songhua¹, SUN Shaohui¹, CHEN Na¹, ZHU Qi¹, CHEN Yu¹, SHE Wenyu², LIU Hui³

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Abstract

Objective To study the relationship between olfactory dysfunction and eosinophila in eosinophilic chronic rhinosinusitis. Methods 45 patients with ECRS, 29 males and 16 females, age range 23 to 65 with average 33.7. Olfactory function was evaluated by T&T method, mucosal tissue specimens were collected at the time of surgery and eosinophil counts were used to identify histologic feature. Spearman’s rank correlation was assessed. Results The olfactory dysfunction was observed in ECRS patients with 2.3±1.9 and correlated with eosinophil counts (253±102)/HP with(r=0.68,P<0.01). Conclusions The olfactory dysfunction in ECRS is correlated with eosinophil counts in olfactory nasal mucosa.

Key words

eosinophilic chronic sinusitis / nasal mucosa / olfactory dysfunction / eosinophills

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ZHAO Songhua, SUN Shaohui, CHEN Na, ZHU Qi, CHEN Yu, SHE Wenyu, LIU Hui. Relationship between olfactory dysfunction and eosinophil counts in eosinophilic chronic sinusitis[J]. Medical Journal of the Chinese People Armed Police Forces. 2015, 26(4): 350-352

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