Histology and biomechanical characteristics of uterine cesarean section (CS) scar in different years postcesarean section

WANG Caixia; GUO Peifen; HU Qingli

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Medical Journal of the Chinese People Armed Police Forces ›› 2015, Vol. 26 ›› Issue (9) : 900-903.

Histology and biomechanical characteristics of uterine cesarean section (CS) scar in different years postcesarean section

WANG Caixia, GUO Peifen, HU Qingli

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Abstract

Objective To study the histological and mechanical characteristics of cesarean uterine scar in different years post cesarean section(CS). Methods Patients were set into two groups according to the interval years post CS. Group 1: the interval periods between the two CS operation day were >1 year and ≤2 years; Group 2: interval >2 years and ≤5 years. Thickness of the LUS was detected by transabdominal ultrasound scan(TAUS) before CS and micrometer screw gauge once the samples of LUS were obtained. Arrangement of muscles (anti-β-actin) and blood vessels (anti-CD34) by immunohistochemistry, tensile strength of the uterine scar tissue were detected as well. Results The thickness of LUS scar were consistent between the groups, no matter what methods were used; muscle and collagen in the uterine scar were disorderly under optical microscopy, collagen content within “Group 1” (39.3±7.1) μg/mg, was significantly higher than “Group 2” (33.3±7.6) μg/mg, P=0.022; there were no significant differences between the tensile strength of the scar tissue. Conclusions The histological and mechanical characteristics of the anterior wall scar of LUS show no significant difference between less or more than 2 years, which needs strenuous efforts to avoid poor uterine wound healing.

Key words

cesarean section / uterine scar / CD34

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WANG Caixia, GUO Peifen, HU Qingli. Histology and biomechanical characteristics of uterine cesarean section (CS) scar in different years postcesarean section[J]. Medical Journal of the Chinese People Armed Police Forces. 2015, 26(9): 900-903

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