Objective To study the significance of high sensitive Creactive protein (CRP) level in the course of development of gestational diabetes mellitus(GDM).Methods Eighty-seven pregnant women were recruited and divided into normal glucose tolerance group (32 cases), gestational impaired glucose tolerance group (30 cases), and GDM group (32 cases).The levels of serum CRP in different groups were detected.60 healthy women who received physical examination during the same period were recruited as control group.Results There was no significant difference in the fasting blood glucose and CRP level between health control group and normal pregnancy group (P<0. 05). The fasting blood glucose and CRP level in gestational impaired glucose tolerance group and GDM group were significantly higher than those in normal pregnancy group (P<0. 05 ) . The fasting blood glucose and CRP level in GDM group were significantly higher than those in gestational impaired glucose tolerance group (P<0. 05) .Conclusions The increase of CRP level can predict the occurrence of GDM.
Key words
c-reactive protein /
gestational diabetes mellitus /
value
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
References
[1] American Diabetes Association.Standards of medical care in diabetes-2010[J].Diabetes Care,2010,33(Suppl 1):S11-S61.
[2] 魏玉梅,杨慧霞. “第六届糖尿病合并妊娠国际会议”纪要[J].中华围产医学杂志,2011,14(7):447-448.
[3] 周晨晨.妊娠期糖尿病监测手段的探讨[J].医学综述,2012,18(9):1394-1395.
[4] 乐 杰.妇产科学[M].7版.北京:人民卫生出版社,2008:151-152.
[5] International Association of Diabetes and Pregnancy Study Groups Consensus Pane1.International association of diabetes and pregnancy study groups recommendations on the diagnosis and classification of hyperglycemia in pregnancy[J].Diabetes Care,2010,33(3):676-682.
[6] 陆晶晶.C反应蛋白的检测及临床意义[J].临床肺科杂志,2009,14(12):1653-1654.
[7] 江 雁.C反应蛋白与妊娠期糖尿病关系的研究进展[J].现代医学,2009,37(1):67-68.
[8] 王红日,林 航,张素英.妊娠期不同糖代谢水平血清C反应蛋白与胰岛素抵抗的关系[J].福建医药杂志,2010,32(5):86-87.
[9] Qiu C,Sorensen T K,Luthy D A,et al. A prospective study of maternal serum C reactive of and risk prote in (CRP) concentrations and risk of gestational diabetes Perinatmellitus[J].Pacdiatr Epidemiol,2004,18(5):377-384.
PDF(525 KB)
