Objective To study the risk factors for coronary heart disease (CHD) in patients with type 2 diabetes mellitus.Methods A total of 216 inpatients with type 2 diabetes mellitus were divided into type 2 diabetes mellitus only group (n=119) and type 2 diabetes mellitus combined with CHD group (n=97). Their values of the urinary microalbumin/creatinine ratio(UACR) and their serum levels of free fatty acid (FFA),homocysteine (Hcy) were measured. The logistic regression model was used to determine the risk factors for CHD.Results The value of UACR and the serum levels of FFA and Hcy were significantly higher in type 2 diabetes mellitus combined with CHD group than in type 2 diabetes mellitus only group[(65.80±7.50) mg/g vs (40.99±6.07)mg/g,P=0.029;(0.80±0.35)mmol/L vs(0.53±0.20)mmol/L,P=0.035;(19.36±6.33)μmol/L vs(12.93±7.07)μmol/L,P=0.033]. Logistic regression analysis showed that FFA (OR=2.335,95%CI:1.770-4.018,P=0.018), UACR(OR=1.166,95%CI:1.082-2.330,P=0.032), and Hcy (OR=2.113,95%CI:1.810-3.770,P=0.026) were the risk factors for CHD.Conclusions FFA,UACR and Hcy are risk factors for CHD in patients with type 2 diabetes mellitus.
Key words
type 2 diabetes mellitus /
coronary heart disease /
free fatty acid /
microalbumin/creatinine ratio /
homocysteine /
risk factor
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