Safety and effect of microincision vitrectomy with bio-glues for retinal holes sealing in rhegmatogenous retinal detachment

WANG Qun; ZHAO Jie; and HOU Baojie

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Medical Journal of the Chinese People Armed Police Forces ›› 2018, Vol. 29 ›› Issue (12) : 1155-1158.

Safety and effect of microincision vitrectomy with bio-glues for retinal holes sealing in rhegmatogenous retinal detachment

WANG Qun, ZHAO Jie, and HOU Baojie

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Abstract

Objective To evaluate the safety and effect of microincision vitrectomy and bio-glue in sealing retinal holes for primary rhegmatogenous retinal detachment.Methods Between June 2014 and June 2017, 21 cases of primary rhegmatogenous retinal detachment patients (21 eyes) were selected from our Department of Ophthalmology. All the 21 patients were given microinvision vitrectomy, during which bio-glue was used to seal the retinal holes. At the end of surgery, a balanced saline solution was used to fill the vitreous cavity. The glue membrane, first-time retinal reattachment rate, corrected visual acuity, intraocular pressure and intraocular inflammatory reaction and complications were observed.Results The bio-glue could adhere fast to the retina during microincision vitrectomy. The bio-glue membrane was absorbed at (13.77±5.13)days postoperatively. All the retinal holes were totally sealed after surgery. The first-time retinal reattachment rate was 100%. At 12 months after microincision vitrectomy, the corrected visual acuity was significantly improved from 0-2.32,average(0.93±0.74),to 0-2.15,average(0.79±0.62). One eye was diagnosed with epiretinal membrane after vitrectomy and was finally given membrane peeling surgery. Two eyes in two cases developed an abnormal intraocular pressure at 7 days after vitrectomy. With the use of Timolol, the pressure returned to normal. During vitrectomy and 12 months of follow-up, there was no obvious inflammation or adverse effect.Conclusions The joint application of vitrectomy and bio-glue can seal retinal holes properly without the use of gas. It can be a new alternative to rehgmatogenous retinal detachment during microincision vitrectomy.

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bio-glue / rehgmatogenous retinal detachment / microincision vitrectomy / retinal hole

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WANG Qun, ZHAO Jie, and HOU Baojie. Safety and effect of microincision vitrectomy with bio-glues for retinal holes sealing in rhegmatogenous retinal detachment[J]. Medical Journal of the Chinese People Armed Police Forces. 2018, 29(12): 1155-1158

References

[1] D’Amico D J. Clinical practice. Primary retinal detachment[J]. N Engl J Med,2008, 359(22): 2346-2354.
[2] Blindbaek S, Grauslund J. Prophylactic treatment of retinal breaks-a systematic review[J]. Acta Ophthalmo, 2015, 93(1): 3-8.
[3] Brinton D A, Wilkinson C P, Hilton G F, et al. Retinal detachment: principles and practice[M]. 3rd ed. San Francisco, CA: Oxford University Press in cooperation with the American Academy of Ophthalmology, 2009.
[4] Wickham L, Ho-Yen G O, Bunce C, et al. Surgical failure following primary retinal detachment surgery by vitrectomy: risk factors and functional outcomes[J]. Br J Ophthalmol, 2011, 95(9):1234-1238.
[5] Mitry D, Awan M A, Borooah S, et al. Surgical outcome and risk stratification for primary retinal detachment repair: results from the Scottish Retinal Detachment study [J]. Br J Ophthalmol, 2012, 96(5):730-734.
[6] Williamson T H, Lee E J, Shunmugam M. Characteristics of rhegmatogenous retinal detachment and their relationship to success rates of surgery [J]. Retina, 2014, 34(7):1421-1427.
[7] Shiraki N, Sakimoto S, Sakaguchi H, et al. Vitrectomy without prone positioning for rhegmatogenous retinal detachments in eyes with inferior retinal breaks[J]. PLoS One,2018,13(1): e0191531.
[8] Wagenfeld L, Zeitz O, Skevas C,et al.Long-lasting endotamponades in vitreoretinal surgery[J].Ophthalmologica, 2010, 224(5):291-300.
[9] Scheerlinck L M, Schellekens P A, Liem A T, et al. Retinal sensitivity following intraocular silicone oil and gas tamponade for rhegmatogenous retinal detachment[J]. Acta Ophthalmol, 2018, march.
[10] Dunn C J, Goa K L. Fibrin sealant: a review of its use in surgery and endoscopy [J]. Drugs, 1999, 58(5): 863-886.
[11] Rodriguez-Merchan E C. Fibrin glue for local haemostasis in haemophilia surgery[J]. Hosp Pract(1995), 2017, 45(5):187-191.
[12] Canonico S. The use of human fibrin glue in the surgical operations[J]. Acta Biomed, 2003, 74: 21-25.
[13] Liao F T, Chang C J. Initial experience with fibrin glue treatment of anal fistulae in children[J]. Am Surg, 2018, 84(6):1105-1109.
[14] Lara F J, Serrano A M, Moreno J U, et al. Platelet-rich fibrin sealant as a treatment for complex perianal fistulas: a multicentre study[J]. J Gastrointest Surg, 2015, 19(2): 360-368.
[15] Chu J K, Miller B A, Bazylewicz M P, et al. Repair of a traumatic subarachnoid-pleural fistula with the percutaneous injection of fibrin glue in a 2-year-old [J].J Neurosurg Pediatr, 2016, 17(1): 1-6.
[16] Cavallo L M, Solari D, Somma T, et al. The awake endoscope-guided sealant technique with fibrin glue in the treatment of postoperative cerebrospinal fluid leak after extended transsphenoidal surgery: technical note [J]. World Neurosurg, 2014, 82(3-4):e479-485.
[17] Abdelkader A. Effect of fibrin glue on corneal lamellar healing and how it correlates to biomechanical properties: biomechanical wavefront analysis and confocal study [J]. Eye Vis (Lond), 2016, 3:15.
[18] Boucher S, Conlon R, Teja S, et al. Fibrin glue versus autologous blood for conjunctival autograft fixation in pterygium surgery[J]. Can J Ophthalmol, 2015, 50(4):269-272.
[19] Tong A Y, Gupta P K, Kim T.Wound closure and tissue adhesives in clear corneal incision cataract surgery[J]. Curr Opin Ophthalmol, 2018, 29(1):14-18.
[20] Narang P, Agarwal A, Kumar D A, et al. Clinical outcomes of the glued intraocular lens scaffold [J]. J Cataract Refract Surg, 2015, 41:1867-1874.
[21] Albala D M, Lawson J H. Recent clinical and investigational applications of fibrin sealant in selected surgical specialties [J]. J Am CollSurg, 2006, 4(4):685-697.
[22] Holladay J T. Proper method for calculating average visual acuity[J]. J Refract Surg, 1997, 13(4):388-391.
[23] Regillo C D, Tornambe P E. Primary retinal detachment repair. Vitreoretinal Disease: The Essentials[M]. New York: Thieme, 1998, 631-646.
[24] Szurman P. Vitreous substitute in retinal detachment surgery-why we need a new tamponade strategy[J]. Klin Monbl Augenheilkd, 2017, 234(9):1094-1102.
[25] Vaziri K, Schwartz S G, Kishor K S, et al. Tamponade in the surgical management of retinal detachment [J]. Clin Ophthalmol, 2016, 10:471-476.
[26] Barr C C, Lai M Y, Lean J S, et al. Postoperative intraocular pressure abnormalities in the silicone study: silicone study report 4[J]. Ophthalmology, 1993, 100(11):1629-1635.
[27] Donati S, Caprani S M, Airaghi G, et al. Vitreous substitutes: the present and the future[J]. Biomed Res Int, 2014,2014:1-12.
[28] Heimann H, Zou X, Jandeck C, et al. Primary vitrectomy for rhegmatogenous retinal detachment: an analysis of 512 cases[J]. Graefe’s Arch Clin Exp Ophthalmol, 2006, 244(1):69-78.
[29] Martinez-castillo V, Boixadera A, Verdugo A, et al. Pars plana vitrectomy alone for the management of inferior breaks in pesudophakic retinal detachment without facedown position[J]. Ophthalmology, 2005, 112(7):1222-1226.
[30] Martinez-Castillo V, Boixadera A, Distefano L, et al. Epiretinal membrane after pars plana vitrectomy for primary pseudophakic or aphakicrhegmatogenous retinal detachment: incidence and outcomes[J]. Retina, 2012, 32(7):1350-1355.
[31] Kunikata H, Nishida K. Visual outcome and complications of 25-gauge vitrectomy for rhegmatogenous retinal detachment; 84 consecutive cases [J]. Eye (Lond), 2010, 24(6):1071-1077.