[1] 贾建平. 提高认知障碍疾病的诊治水平任重而道远[J] .中华医学杂志, 2018,98(13): 961-962.
[2] 贾建平,唐 毅,王 芬. 重视阿尔茨海默病的痴呆前阶段[J].中华神经科杂志, 2013, 46(1): 2-4.
[3] Wattmo C, Minthon L, Wallin  K. Mild versus moderate stages of Alzheimer’s disease: three-year outcomes in a routine clinical setting of cholinesterase inhibitor therapy[J]. Alzheimer’s Res & Ther, 2016, 8(7): 1-15.
[4] Meguro K, Ouchi Y, Akanuma K, et al. Donepezil can improve daily activities and promote rehabilitation for severe Alzheimer’s patients in long-term care health facilities[J].BMC Neurol, 2014,14:243-249.
[5] Moss D E, Perez R G, Kobayashi H. Cholinesterase inhibitor therapy in Alzheimer’s: the limits and tolerability of irreversible CNS-selective Acetylcholinesterase inhibition in primates[J]. Alzheimers Dis, 2017,55(3):1285-1294.
[6] Rosenberg P B, Lanctt K L, Drye L T, et al. Safety and efficacy of methylphenidate for apathy in Alzheimer's disease: a randomized, placebo-controlled trial[J]. Clin Psychiatry, 2013,74(8):810-816.
[7] Chen R, Chan P T, Chu H, et al. Treatment effects between monotherapy of donepezil versus combination with memantine for Alzheimer disease: a meta-analysis[J]. PLoS One, 2017,12(8):e0183586.
[8] Matsunaga S, Kishi T, Iwata N. Combination therapy with cholinesterase inhibitors and memantine for Alzheimer’s disease: a systematic review and meta-analysis[J]. Alzheimers Dement, 2014,10(4):859-860.
[9] Tang M X,Jacobs D,Stern Y,et al.Effect of oestrogen during menopause on risk and age at onset of Alzheimer’s disease[J].Lancet,1996,348(9025):429-432.
[10] Shao H, Breitner J C, Whitmer R A, et al. Hormone therapy and Alzheimer disease dementia: new findings from the cache county study[J]. Neurology, 2012, 79(18):1846-1852.
[11] Yarchoan M, Arnold S E. Repurposing diabetes drugs for brain insulin resistance in Alzheimer disease[J].Diabetes, 2014, 63(7):2253-2261.
[12] Freiherr J, Hallschmid M, Frey W H, et al. Intranasal insulin as a treatment for Alzheimer’s disease: a review of basic research and clinical evidence[J]. CNS Drugs, 2013, 27(7):505-514.
[13] Dysken M W, Sano M, Asthana S, et al. Effect of vitamin E and memantine on functional decline in Alzheimer disease: the TEAM-AD VA cooperative randomized trial[J]. JAMA, 2014,311(1):33-44.
[14] Kryscio R J, Abner E L, Caban-Holt A, et al. Association of antioxidant supplement use and dementia in the prevention of Alzheimer’s disease by vitamin E and selenium trial (PREADViSE)[J].JAMA Neurol, 2017,74(5):567-573.
[15] Lemere C A. Immunotherapy for Alzheimer’s disease: hoops and hurdles[J]. Mol Neurodegener, 2013,8(36):1-6.
[16] Agadjanyan M, Petrovsky N, Ghochikyan A. A fresh perspective from immunologists and vaccine researchers: active vaccination strategies to prevent and reverse Alzheimer’s disease[J]. Alzheimers Dement, 2015,11(10):1246-1259.
[17] Bateman R. Alzheimer’s disease and other dementias: advances in 2014[J].Lancet Neurol, 2015,14(1):4-6.
[18] Wisniewski T, Goi F. Immunotherapeutic approaches for Alzheimer’s disease[J]. Neuron, 2015,85(6):1162-1176.
[19] Counts S, Ray B, Mufson E J, et al. Intravenous immunoglobulin (IVIG) treatment exerts antioxidant and neuropreservatory effects in preclinical models of Alzheimer’s disease[J]. J Clin Immunol, 2014,34(1): S80-S85.
[20] Chua K K, Wong A, Kwan P, et al. The efficacy and safety of the Chinese herbal medicine Di-Tan decoction for treating Alzheimer’s disease: protocol for a randomized controlled trial[J]. Trials, 2015,16(1):199-205.
[21] Gauthier S, Schlaefke S. Efficacy and tolerability of Ginkgo biloba extract EGb 761 in dementia: a systematic review and meta-analysis of randomized placebo-controlled trials[J]. Clin Interv Aging, 2014,9:2065-2077.
[22] Yang W T, Zheng X W, Chen S, et al. Chinese herbal medicine for Alzheimer's disease: clinical evidence and possible mechanism of neurogenesis[J]. Biochem Pharmacol, 2017,141:143-155.
[23] Kamal Z, Ullah F, Ayaz M, et al. Anticholinesterse and antioxidant investigations of crude extracts, subsequent fractions, saponins and flavonoids of atriplex laciniata L: potential effectiveness in Alzheimer’s and other neurological disorders[J]. Biol Res, 2015, 48(1):21-31.
[24] Hsu W Y, Ku Y, Zanto T P, et al. Effects of non-invasive brain stimulation on cognitive function in healthy aging and Alzheimer’s disease: a systematic review and meta-analysis[J]. Neurobiol Aging, 2015, 36(8):2348-2359.
[25] Zhang C, Hu W H, Wu D L, et al. Behavioral effects of deep brain stimulation of the anterior nucleus of thalamus, Entorhinal cortex and fornix in a rat model of Alzheimer’s disease[J]. Chinese Med J, 2015, 128(9):1190-1195.
[26] Tremblay S, Lepage J F, Latulipe-Loiselle A, et al. The uncertain outcome of prefrontal tDCS[J]. Brain Stimulation, 2014, 7(6):773-783.
[27] Choi J, Twamley E W. Cognitive rehabilitation therapies for Alzheimer’s disease: a review of methods to improve treatment engagement and self-efficacy[J]. Neuropsychol Rev, 2013, 23(1):48-62.
[28] Surmeli T, Eralp E, Mustafazade I, et al. Quantitative EEG neurometric analysis-guided neurofeedback treatment in postconcussion syndrome (PCS): forty cases. How is neurometric analysis important for the treatment of PCS and as a biomarker[J]. Clin EEG Neurosci,2016, 48(3):217-230.
[29] Ibarria M, Alegret M, Valero S, et al. Beneficial effects of an integrated psychostimulation program in patients with Alzheimer’s disease[J]. JAD , 2016, 50(2):559-566.
[30] Reilly J. How to constrain and maintain a lexicon for the treatment of progressive semantic naming deficits: principles of item selection for formal semantic therapy[J].Neuropsychol Rehabil,2015,26(1):126-156.
[31] Figueiro M G, Plitnick B A, Lok A, et al. Tailored lighting intervention improves measures of sleep, depression, and agitation in persons with Alzheimer’s disease and related dementia living in long-term care facilities[J]. Clin Int Aging,2014, 9:1527-1537.
[32] Hanford N, Figueiro M. Light therapy and Alzheimer’s disease and related dementia: past, present, and future[J]. JAD, 2013, 33(4):913-922.
[33] Osman S E, Tischler V, Schneider J. ‘Singing for the Brain’: a qualitative study exploring the health and well-being benefits of singing for people with dementia and their carers[J]. Dementia (London), 2016, 15(6):1326-1339.
[34] Stéphane G,, Charras K, Berard A, et al. An overview of the use of music therapy in the context of Alzheimer's disease: a report of a French expert group.[J]. Dementia, 2013, 12(5):619-634.
[35] Raglio A, Filippi S, Bellandi D, et al. Global music approach to persons with dementia: evidence and practice[J]. Clin Int Aging,2014, 9:1669-1676.
[36] Zhou J, Peng W, Xu M, et al. The effectiveness and safety of acupuncture for patients with Alzheimer disease: a systematic review and Meta-Analysis of randomized controlled trials[J]. Medicine,2015,94(22):e933.
[37] Paoli A, Bianco A, Damiani E, et al. Ketogenic diet in neuromuscular and neurodegenerative diseases[J]. Bio Med Res Int, 2014,2014:1-10.
[38] Walczyk T, Wick J Y. The ketogenic diet: making a comeback[J]. The Consultant Pharmacist, 2017, 32(7):388-396.
[39] Holthoff V A, Marschner K, Scharf M, et al. Effects of physical activity training in patients with Alzheimer’s dementia: results of a pilot RCT study[J]. PLoS One, 2015,10(4):e0121478.
[40] Smallfield S, Heckenlaible C. Effectiveness of occupational therapy interventions to enhance occupational performance for adults with Alzheimer’s disease and related major neurocognitive disorders: a systematic review[J]. Am J Occup Ther, 2017,71(5):7105180010p1-7105180010p9.