Effect of short-term exercise interventions on preoperative blood glucose in patients with type 2 diabetes mellitus: a pilot study

GAO Xueyan; GAO Hongkai; GAO Yanhong

PDF(1035 KB)

Medical Journal of the Chinese People Armed Police Forces ›› 2019, Vol. 30 ›› Issue (5) : 431-436.

Effect of short-term exercise interventions on preoperative blood glucose in patients with type 2 diabetes mellitus: a pilot study

GAO Xueyan^1,2, GAO Hongkai², GAO Yanhong³

Author information +

History +

Abstract

Objective To tentatively investigate the effect of short-term exercise interventions on preoperative blood glucose in patients with type 2 diabetes mellitus (T2DM).Methods Forty-five patients with T2DM scheduled for surgery were randomly divided into the moderate-intensity intermittent exercise group, low-intensity continuous exercise group and control group, with fifteen cases in each. The two exercise groups were subjected to 3-5 days of exercise interventions of different intensities and in different modes. Under the same conditions, the control group received nothing more than preoperative basic care and routine education. In order to observe the effect of short-term glycemic control,the biochemical examination and the 24-hour continuous glucose monitoring system (CGMS) were used to evaluate the levels of FPG, PPG, Fins, HOMA-IR and lnIS of each subject before and after the intervention.Results (1) After three days of exercise intervention, the overall glycemic compliance rate of the moderate-intensity exercise group was higher than that of the control group (P<0.05). Except for FPG, all the other glycemic indexes were lower than those of the control group (P<0.05). The effect of exercise on PPG improvement in patients of the moderate intermittent exercise group was even more significant than in the low-intensity continuous exercise group (P<0.05). (2) Five days after the exercise intervention program, the levels of PPG were lower in the low-intensity continuous exercise group than that in the control group (P<0.05). With the exception of FPG, all the other glycemic indexes were more significantly improved in the moderate intermittent exercise group than that in the control group(P<0.05).Conclusion The short-term exercise intervention program has a positive effect on preoperative glycemic control in T2DM inpatients.

Key words

exercise intervention / type 2 diabetes mellitus / perioperative period / glycemic management

Cite this article

EndNote

Ris (Procite)

Bibtex

Download Citations

GAO Xueyan, GAO Hongkai, GAO Yanhong. Effect of short-term exercise interventions on preoperative blood glucose in patients with type 2 diabetes mellitus: a pilot study[J]. Medical Journal of the Chinese People Armed Police Forces. 2019, 30(5): 431-436

References

[1] Duggan E W, Carlson K, Umpierrez G E. Perioperative hyperglycemia management: an update[J]. Anesthesiology, 2017, 126(3):547-560.
[2] Leung V, Ragbir-Toolsie K. Perioperative management of patients with diabetes[J]. Health Servi Insights, 2017, 10(8):1-5.
[3] 高卉.围术期血糖管理专家共识(快捷版)[J]. 临床麻醉学杂志, 2016, 32(1):93-95.
[4] 曾龙驿. 新诊断超重或肥胖且HbA1c≥9%的2型糖尿病患者首选生活方式干预[J]. 医学与哲学(B), 2015, 36(4): 19-21,54.
[5] Colberg S R, Sigal R J, Yardley J E, et al. Physical activity/exercise and diabetes: a position statement of the American Diabetes Association[J]. Diabetes Care, 2016, 39(11):2065-2079.
[6] Mikus C R, Oberlin D J, Libla J L, et al. Lowering physical activity impairs glycemic control in healthy volunteers[J]. Med Sci Sports Exerc, 2012, 44(2):225-231.
[7] Kirwan J P, Solomon T P, Wojta D M, et al. Effects of 7 days of exercise training on insulin sensitivity and responsiveness in type 2 diabetes mellitus[J]. Am J Physiol Endocrinol Metab, 2009, 297(1):151-156.
[8] 尚画雨,张丹,王瑞元,等.高强度间歇训练对糖尿病作用效果研究进展[J].中国康复医学杂志,2014,29(8):793-798.
[9] 尤黎明, 吴瑛. 内科护理学[M].北京:人民卫生出版社, 2013: 585-586.
[10] O’Hagan C, Vito G D, Boreham C A. Exercise prescription in the treatment of type 2 diabetes mellitus[J]. Sports Med, 2013, 43(1):39-49.
[11] 郭晓蕙,孙子林.中国糖尿病运动治疗指南[M]. 北京:中华医学电子音像出版社,2013:7-9.
[12] Ciolac E G, Mantuani S S, Neiva C M, et al. Rating of perceived exertion as a tool for prescribing and self regulating interval training: a pilot study [J]. Biol Sport, 2015, 32(2):103-108.
[13] Buchleitner A M, Martínez-Alonso M, Hernández M, et al. Perioperative glycaemic control for diabetic patients undergoing surgery[J].Cochrane Database Syst Rev, 2012,12(9) :CD007315.
[14] Yanai H, Adachi H, Masui Y, et al. Exercise therapy for patients with type 2 diabetes: a narrative review[J]. J Clin Med Res, 2018, 10(5):365-369.
[15] Bird S R, Hawley J A. Update on the effects of physical activity on insulin sensitivity in humans[J]. BMJ Open Sport Exerc Med, 2016, 2(1):e000143.
[16] Francois M E, Little J P. Effectiveness and safety of high-intensity interval training in patients with type 2 diabetes [J]. Diabetes Spectr, 2015, 28(1): 39-44.
[17] Nosso G, Lupoli R, Saldalamacchia G, et al. Diabetes remission after bariatric surgery is characterized by high glycemic variability and high oxidative stress[J]. Nutr Metab Cardiovasc Dis, 2017,27(11):949-955.
[18] Ceriello A, Testa R, Genovese S. Clinical implications of oxidative stress and potential role of natural antioxidants in diabetic vascular complications[J]. Nutr Metab Cardiovasc Dis, 2016, 26(4):285-292.
[19] Zhou J, Jia W, Bao Y, et al. Glycemic variability and its responses to intensive insulin treatment in newly diagnosed type 2 diabetes[J]. Med Sci Monit, 2008, 14(11):CR552-558.
[20] Buresh R, Berg K. Exercise for the management of type 2 diabetes mellitus. Factors to consider with current guidelines[J]. J Sports Med Phys Fitness, 2018,58(4):510-524.
[21] Bailey K J, Little J P, Jung M E. Self-Monitoring using continuous glucose monitors with real-time feedback improves exercise adherence in individuals with impaired blood glucose: a pilot study[J]. Diabetes Technol Ther, 2016, 18(3):185-193.