Correlations between body composition of early pregnant women and macrosomia risk

ZHANG Can; LIU Jie; ZHANG Haiyan; FAN Zhonggui; LUO Li; XU Hongxia

PDF(727 KB)

Medical Journal of the Chinese People Armed Police Forces ›› 2019, Vol. 30 ›› Issue (9) : 764-768.

ORIGINAL ARTICLES

Correlations between body composition of early pregnant women and macrosomia risk

ZHANG Can^1,2, LIU Jie¹, ZHANG Haiyan², FAN Zhonggui², LUO Li², XU Hongxia¹

Author information +

History +

Abstract

Objective To explore the association between body composition of early pregnant women and macrosomia risk.Methods We retrospectively included 1697 pregnant women who had given birth in Yongchuan Maternity and Child Health Hospital of Chongqing between January and September in 2016. Macrosomia related risk factors as well as body composition of early pregnant women were investigated and follow-up was performed until the cessation of pregnancy. Logistic regression analysis was used to explore the association between macrosomia and potential risk factors, including body composition of early pregnant women.Results BMI of early pregnancy, body fat weight and body fat percentage were independent risk factors for macrosomia. Fat-free mass was an independent protective factor. Early pregnant women with BMI≥28 were 3.75 times as likely to have macrosomic newborns as those with normal BMI (18.5-23.9). Similarly, pregnant women with fat weight greater than 0.28 times body weight were 4.21 times as vulnerable as those with fat weight less than 0.2 times body weight. Pregnant women with a body fat percentage≥30% were 1.86 times as vulnerable as those with a body fat percentage＜30%. Pregnant women with fat-free mass greater than 0.8 times body weight had a 76% decreased risk for macrosomic newborns.Conclusions BMI and body composition of early pregnancy are associated with macrosomia risk. Nutrition and exercise interventions are recommended in those early pregnant women with obesity and excessive body fat to reduce the risk of macrosomia.

Key words

early pregnancy / body composition / body fat percentage / fat-free mass / macrosomia

Cite this article

EndNote

Ris (Procite)

Bibtex

Download Citations

ZHANG Can, LIU Jie, ZHANG Haiyan, FAN Zhonggui, LUO Li, XU Hongxia. Correlations between body composition of early pregnant women and macrosomia risk[J]. Medical Journal of the Chinese People Armed Police Forces. 2019, 30(9): 764-768

References

[1] American College of Obstetricians and Gynecologists’ Committee on Practice Bulletins -Obstetrics. Practice bulletin No. 173: fetal macrosomia[J]. Obstet Gynecol,2016, 128(5): e195-e209.
[2] Hamilton B E, Martin J A, Osterman M J, et al.Births:final data for 2014[J].Natl Vital Stat Rep,2015,64(12):1-64.
[3] 于冬梅, 翟凤英, 赵丽云, 等.中国2006年巨大儿发生率及其影响因素[J].中国儿童保健杂志,2008,16(1):11-13.
[4] King J R, Korst L M, Miller D A, et al. Increased composite maternal and neonatal morbidity associated with ultrasonographically suspected fetal macrosomia[J]. Matern Fetal Neonatal Med, 2012, 25(10):1953-1959.
[5] 漆洪波, 郑静. 美国妇产科医师学会“巨大儿指南(2016)”要点解读[J].重庆医科大学学报,2017,42(8): 926-928.
[6] Henriksen T .The macrosomic fetus: a challenge in current obstetrics[J]. Acta Obstet Gynecol Scand, 2008, 87(2):134-145.
[7] Walsh J M, McAuliffe F M. Prediction and prevention of the macrosomic fetus[J]. Eur J Obstet Gynecol Reprod Biol, 2012, 162(2):125-130.
[8] Jolly M C, Sebire N J, Harris J P, et al. Risk factors for macrosomia and its clinical consequences: a study of 350,311 pregnancies[J]. Eur J Obstet Gynecol Reprod Biol, 2003, 111(1): 9-14.
[9] Cedergren M. Effects of gestational weight gain and body mass index on obstetric outcome in Sweden[J]. Int J Gynaecol Obstet, 2006, 93(3): 269-274.
[10] Lukaski H C, Johnson P E, Bolonchuk W W, et al. Assessment of fat-free mass using bioelectrical impedance measurements of the human body [J]. Am J Clin Nutr, 1985, 41(4): 810-817.
[11] Villar J, Cogswell M, Kestler E, et al. Effect of fat and fat-free mass deposition during pregnancy on birth weight[J]. Am J Obstet Gynecol, 1992, 167(5): 1344-1352.
[12] 高洪娟,郝敏, 樊金荣, 等. 妊娠不同时期孕妇体成分分析的临床价值[J]. 中华临床医师杂志,2016,10(14):2088-2092.
[13] Butte N F, Ellis K J, Wong W W, et al. Composition of gestational weight gain impacts maternal fat retention and infant birth weight[J]. Am J Obstet Gynecol, 2003, 189(5):1423-1432.
[14] Lederman S A, Paxton A , Heymsfield S B, et al. Maternal body fat and water during pregnancy: do they raise infant birth weight [J]. Am J Obstet Gynecol, 1999, 180(1 Pt 1):235-240.
[15] Gernand A D, Christian P, Paul R R, et al.Maternal weight and body composition during pregnancy are associated with placental and birth weight in rural Bangladesh[J]. J Nutr,2012, 142(11): 2010-2016.
[16] 袁丽娟.妊娠期糖尿病孕妇体成分与新生儿体重关系的研究[D].苏州:苏州大学,2016.
[17] 赵金梅,彭艳艳,王海庚, 等. 妊娠期糖尿病孕妇孕期体成分对妊娠结局的影响[J]. 中国生育健康杂志,2017,28(2):152-154.
[18] 徐庆,张英,刘钊, 等. 生物电阻抗法分析分娩巨大儿妇女妊娠期体成分[J]. 解放军医学院学报,2016,37(11):1132-1135.
[19] Forsum E, Sadurskis A, Wager J. Resting metabolic rate and body composition of healthy Swedish women during pregnancy[J]. Am J Clin Nutr, 1988, 47(6):942-947.
[20] Liu P, Xu L, Wang Y, et al. Association between perinatal outcomes and maternal pre-pregnancy body mass index [J]. Obes Rev, 2016,17(11): 1091-1102.
[21] 史琳,陈鹏, 杨红梅,等. 孕妇体质量及其他因素与分娩巨大儿的相关性研究[J].实用妇产科杂志,2017,33(6): 453-458.