Epidemiological investigations of outbreaks of human adenovirus associated respiratory diseases in military units

TANG Fang; ZHANG Zaizhong; WANG Xiaoqin; ZHU Guang; FU Feixiang; CAO Dekang

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Medical Journal of the Chinese People Armed Police Forces ›› 2020, Vol. 31 ›› Issue (5) : 373-377.

ORIGINAL ARTICLES

Epidemiological investigations of outbreaks of human adenovirus associated respiratory diseases in military units

TANG Fang¹, ZHANG Zaizhong², WANG Xiaoqin¹, ZHU Guang¹, FU Feixiang¹, CAO Dekang¹

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Abstract

Objective To analyze the epidemiology of outbreaks and clinical characteristics of respiratory diseases caused by human adenovirus (HAdV) in military units so as to provide data for disease prevention and control. Methods Data on respiratory adenovirus outbreaks between 2009 and 2017 was collected from PubMed and Wanfang Database. The epidemiologic and clinical data and the serotypes of adenovirus were also analyzed. Results The dominating serotypes of adenovirus were 7 and 55, which accounted for 47.11%(1782/3783) and 30.11% (1139/3783) of the total cases of outbreaks, respectively. There were 10 outbreaks related to serotype 7, and 54.02% of the 1020 cases were positive. There were 5 outbreaks related to serotype 55, and 90.10% of the cases (437/485) were positive. The peak time was in 2013, with four outbreaks. Seasonal outbreaks mostly occurred in spring and winter, or to be more specific, between December and March. In terms of regional distribution, Henan Province had the largest number of outbreaks. The high-risk populations were new recruits, among whom the number of outbreaks was 18. The clinical features of adenovirus infection were fever (50.83%-100.00%), pharyngeal hyperemia(37.91%-100.00%), cough(48.17%-95.45%), sore throat (57.14%-87.00%) and expectoration(15.66%-85.23%). Conclusions HAdV has become one of the main pathogenic microorganisms, which induces acute respiratory diseases in the military in China. It is necessary to reinforce epidemic surveillance to curb the spread of the disease.

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respiratory adenovirus / outbreak / epidemiology / clinical characteristics / investigation

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TANG Fang, ZHANG Zaizhong, WANG Xiaoqin, ZHU Guang, FU Feixiang, CAO Dekang. Epidemiological investigations of outbreaks of human adenovirus associated respiratory diseases in military units[J]. Medical Journal of the Chinese People Armed Police Forces. 2020, 31(5): 373-377

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