MR neuroimaging features of multiple system atrophy-parkinsonian type

ZHENG Kuihong; ZHANG Jing; HU Jianfeng; LU Qiaohui; LI Xiaojuan

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Medical Journal of the Chinese People Armed Police Forces ›› 2021, Vol. 32 ›› Issue (7) : 573-576.

ORIGINAL ARTICLES

MR neuroimaging features of multiple system atrophy-parkinsonian type

ZHENG Kuihong, ZHANG Jing, HU Jianfeng, LU Qiaohui, LI Xiaojuan

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Abstract

Objective To analyze slit-like putaminal hypointensity on T₂-weighted imaging, and putaminal hypointensity on DWI,pontine atrophy and middle cerebellar peduncle atrophy in patients with multiple system atrophy-parkinsonian type(MSA-P). Methods Twenty patients with MSA-P and another 20 age-matched healthy subjects were enrolled. The scanning protocol included FSE T₂WI sequences on standard sagittal and axial views,T₁ FLAIR sequence on the axial view,and diffusion weighted imaging(DWI) sequence on the axial view. Atrophy of the pons and middle cerebellar peduncle,slit-like putaminal hypointensity on T₂-weighted imaging,and putaminal hypointensity on DWI were all evaluated. Results Puaminal hypointensity on DWI was observed in 90%(18/20)of the patients,slit-like putaminal hypointensity on T₂-weighted imaging in 70% (14/20), unilateral or bilateral middle cerebellar peduncle atrophy in 40%(8/20),and pontine atrophy in 30%(6/20).The slit-like putaminal hypointensity on T₂-weighted imaging and putaminal hypointensity on DWI were significantly different between MSA-P patients and controls (P＜0.01). Conclusions The slit-like putaminal hypointensity on T₂-weighted imaging and putaminal hypointensity on DWI are more common among MSA-P patients. The incidence of putaminal hypointensity on DWI is higher than that of slit-like putaminal hypointensity on T₂-weighted imaging in patients with MSA-P.

Key words

magnetic resonance imaging, diffusion weighted / putaminal / multiple system atrophy,Parkinsonian type / Parkinson disease

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ZHENG Kuihong, ZHANG Jing, HU Jianfeng, LU Qiaohui, LI Xiaojuan. MR neuroimaging features of multiple system atrophy-parkinsonian type[J]. Medical Journal of the Chinese People Armed Police Forces. 2021, 32(7): 573-576

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