Curative effect of enteral nutrition therapy in rapid recovery after radical resection of esophageal cancer

GU Jinling; GONG Taiqian; DI Shouyin; JIN huiyu; FAN Boshi; WANG Qian; WANG Lijiao

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Medical Journal of the Chinese People Armed Police Forces ›› 2022, Vol. 33 ›› Issue (1) : 27-29.

Curative effect of enteral nutrition therapy in rapid recovery after radical resection of esophageal cancer

GU Jinling, GONG Taiqian, DI Shouyin, JIN huiyu, FAN Boshi, WANG Qian, WANG Lijiao

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Abstract

Objective To retrospectively analyze the effect of enteral nutrition therapy on patients' rehabilitation after radical resection of esophageal cancer. Methods The clinical data on 60 patients undergoing radical esophageal cancer surgery in our hospital between January 2019 and June 2020 was retrospectively analyzed. A jejunostomy tube was placed intraoperatively. The enteral nutrition infusion rate was increased from 20 ml/h to 100 ml/h and the enteral nutrient solution dosage was increased from 500 ml/d to 1000 ml/d on d1-d7 postoperatively. Blood nutrition indexes, postoperative nutrition-related complications, fasting time, bed rest time, indwelling time of the jejunal nutrition tube, and average hospital stay were analyzed. Results Levels of total protein (TP) and prealbumin (PAB) were decreased one day after surgery (POD1), but they were increased on POD3 and POD7 compared with POD1. The albumin level hardly changed over these days. The rate of nutrition-related complications was 23.30%, with one patient developing anastomotic fistula. The patients' average fasting time was (5.52±0.50) days after operation, the average bed rest time was (35.78±7.33) hours, the average postoperative tube indwelling time was (47.70±15.52) days, and the average postoperative hospital stay was (9.60±2.20) days. Conclusions Enteral nutrition therapy after radical resection of esophageal cancer is safe and effective, which can facilitate patients' recovery from surgery.

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enteral nutrition therapy / esophageal cancer / jejunostomy / accelerated rehabilitation surgery

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GU Jinling, GONG Taiqian, DI Shouyin, JIN huiyu, FAN Boshi, WANG Qian, WANG Lijiao. Curative effect of enteral nutrition therapy in rapid recovery after radical resection of esophageal cancer[J]. Medical Journal of the Chinese People Armed Police Forces. 2022, 33(1): 27-29

References

[1] Chen W, Zheng R, Baade P D, et al. Cancer statistics in China, 2015[J]. CA Cancer J Clin, 2016,66(2):115-132.
[2] 王泉, 李大华, 张曼, 等. 食管癌住院患者营养风险筛查及营养不良状况对生活质量和预后的影响[J]. 现代生物医学进展, 2021,21(11):2094-2098.
[3] 王沛如, 罗泽槟, 张佳, 等. 食管癌患者围放疗期营养管理指南的质量评价[J]. 中华护理杂志, 2021,56(5):767-774.
[4] 裴文晔, 于玲, 姜桂春. 食管癌术后早期肠内营养支持的临床效果[J]. 中国医科大学学报, 2021,50(6):544-547.
[5] Shen Y, Zhou Y, He T, et al. Effect of preoperative nutritional risk screening and enteral nutrition support in accelerated recovery after resection for esophageal cancer[J]. Nutrition and Cancer, 2021,73(4):165-168.
[6] 刘小林, 蒋明, 贾辉, 等. 食管癌术后家庭肠内营养治疗效果分析[J]. 肿瘤药学, 2020,10(1):112-115.
[7] 贺宇彤, 梁迪, 杜灵彬, 等. 5283例食管癌患者的临床特征和生存:中国6个地区18家医院的多中心研究[J]. 癌症, 2021,40(3):113-126.
[8] 席晓莉, 何天娇, 张春艳, 等. 肠内营养支持治疗对老年晚期食管癌患者的临床应用研究[J]. 实用医院临床杂志, 2020,17(1):151-154.
[9] 陆文玉, 徐晓晖. 对食管癌患者术后肠内营养的观察与护理[J]. 中国医药指南, 2019,17(28):199-200.
[10] 舒心, 李广欣, 朱曦龄, 等. 自体CIK细胞联合同步放化疗治疗局部晚期食管癌的临床研究[J]. 现代肿瘤医学, 2015,23(10):1376-1380.
[11] 胡梦雪, 高红婷, 宁智鹏, 等. 帕博利珠单抗单药与化疗二线治疗晚期或转移性食管癌的成本-效果分析[J]. 中国医院药学杂志, 2021,15(1):8.
[12] Mao Y S, Gao S G, Wang Q, et al. Epidemiological characteristic and current status of surgical treatment for esophageal cancer by analysis of national registry database[J]. Chi J Oncol, 2020,42(3):365-368.
[13] 缪薇菁, 俞晓艳, 顾爱琴, 等. 食管癌微创术后肠内营养治疗504例疗效分析[J]. 肿瘤学杂志, 2019,25(5):450-452.
[14] 吴菁菁, 黄琳. 空肠营养管对食管癌三野术后患者营养状况改善的研究[J]. 黔南民族医专学报, 2020,33(4):279-281.
[15] 何沁蔓, 彭毅, 董云娅, 等. 早期肠内营养对结直肠癌根治术患者胃肠功能恢复的影响[J]. 局解手术学杂志, 2021,30(9):792-795.
[16] 李晋, 唐永钦, 章敢. 肠外营养与肠内营养支持对根治性全胃切除术后胃肠功能的影响[J]. 遵义医学院学报, 2018,41(3):348-352.
[17] Chen W, Jiang H, Zhou Z Y, et al. Is omega-3 fatty acids enriched nutrition support safe for critical ill patients? A systematic review and meta-analysis[J]. Nutrients, 2014,6(6):2148-2164.
[18] Varadhan K K, Neal K R, Dejong C H, et al. The enhanced recovery after surgery (ERAS) pathway for patients undergoing major elective open colorectal surgery: a meta-analysis of randomized controlled trials[J]. Clin Nutr, 2010,29(4):434-440.
[19] 周燕, 卫妙蓉, 陈佳, 等. 早期肠内营养和延期肠内营养对重型颅脑外伤患者术后营养状况和并发症的影响[J]. 解放军护理杂志, 2017,34(21):16-19.
[20] 汤亲青, 乐建军, 曹先东. 胃癌术后应用肠内营养制剂的对比研究[J]. 肠外与肠内营养, 2021,28(3):147-151.