Clinic features of and risk factors for symptomatic deep vein thrombosis after total knee arthroplasty

LIU Xiaoyang; YIN Xinghua; DAI Li; CHENG Yang

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Medical Journal of the Chinese People Armed Police Forces ›› 2022, Vol. 33 ›› Issue (3) : 222-225.

ORIGINAL ARTICLES

Clinic features of and risk factors for symptomatic deep vein thrombosis after total knee arthroplasty

LIU Xiaoyang¹, YIN Xinghua², DAI Li¹, CHENG Yang¹

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Abstract

Objective To investigate the clinic features and risk factors for symptomatic deep vein thrombosis (DVT) patients after total knee arthroplasty (TKA). Methods A total of 8162 patients undergoing TKA were included in this study. Cases of symptomatic DVT and pulmonary thromboembolism (PTE) were recorded. The association of age, body mass index ( BMI), duration of surgery, a history of hypertension and diabetes, and preoperative serum levels of uric acid, cholesterol,triglyceride and D-dimer with symptomatic DVT was analyzed. Results Sixty-five patients(0.80%)presented with symptomatic DVT, which occurred within median 3 days postoperatively. These cases included 48 cases of distal DVT (73.85%) and 17 cases of proximal DVT(26.15%). There were 5 cases of pulmonary thromboembolism (PTE) after TKA, only one of whom was at high risk. The preoperative serum levels of uric acid in symptomatic DVT patients were significantly higher than those of other patients,indicating correlations (OR=2.532; 95% CI=1.207-5.310;P=0.014) between the preoperative serum levels of uric acid and symptomatic DVT. Conclusions Postoperative DVT can hardly be prevented despite conventional precautions. An increased preoperative serum level of uric acid is a risk factor for symptomatic DVT after TKA. Therefore, effective preventive measures are needed for these patients.

Key words

total knee arthroplasty / deep vein thrombosis / pulmonary thromboembolism

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LIU Xiaoyang, YIN Xinghua, DAI Li, CHENG Yang. Clinic features of and risk factors for symptomatic deep vein thrombosis after total knee arthroplasty[J]. Medical Journal of the Chinese People Armed Police Forces. 2022, 33(3): 222-225

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