Meta-analysis of only surgical treatment of ovarian immature teratoma

LIU Chuanli; LIU Jinlong; CHEN Xiao; ZHANG Yan; CHEN Jun; SUN Yang; WU Siyu

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Medical Journal of the Chinese People Armed Police Forces ›› 2023, Vol. 34 ›› Issue (6) : 461-464.

Meta-analysis of only surgical treatment of ovarian immature teratoma

LIU Chuanli¹, LIU Jinlong², CHEN Xiao¹, ZHANG Yan¹, CHEN Jun¹, SUN Yang¹, WU Siyu¹

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Abstract

Objective To systematically evaluate the safety of the only surgical treatment for patients with ovarian immature teratoma (IT). Methods Pubmed, The Cochrane Library, Web of Science, CNKI, WangFang Data were electronically searched to collect studies on the prognostic outcomes of patients with pure ovarian immature teratoma treated only by surgery and followed up strategy from January 1st, 1990 to February 16th, 2022. Four reviewers independently screened literature, extracted data, and assessed the risk of bias of included studies. Meta-analysis was then performed with STATA software. Results A total of 3 non-randomized cohort studies and 5 case report studies involving 201 patients were included. Most of the patients were in the early stage. twenty-one patients had relapse, and meta-analysis showed that the relapse rate (95%CI) was 5.2%(2.0%,9.4%). In patients with stageⅠ G₂/G₃ pure ovarian IT, the relapse rate (95%CI) was 6.1%(0.3%,16.0%). Three patients died. Conclusions More high-quality studies are needed to determine whether patients with stage Ⅰ G₂/G₃ pure ovarian IT can be treated with surgery alone.

Key words

ovarian immature teratoma / surgery / follow up / relapse / pathological grading / meta-analysis

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LIU Chuanli, LIU Jinlong, CHEN Xiao, ZHANG Yan, CHEN Jun, SUN Yang, WU Siyu. Meta-analysis of only surgical treatment of ovarian immature teratoma[J]. Medical Journal of the Chinese People Armed Police Forces. 2023, 34(6): 461-464

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