Objective To evaluate the early warning indexes related with renal function impairment in recruit training.Methods A total of 126 recruits of mobile forces were selected as research targets. According to the training program, they concentrated on physical training for 2 months and carried out follow-up regular inspection. The 6 test time points were the beginning of the training, 3 days of training, 1 week, 2 weeks, 1 month and 2 months of training. After getting up, the renal function, urine routine test, urine micro protein and other indexes were measured.Results Urinary microprotein significantly increased after 2 weeks [(20.78±4.45) mg/L], 1 month [(21.62±5.66) mg/L] and 2 months [(21.62±5.66) mg/L], and the changes of serum creatinine (Cr) and serum urea nitrogen (BUN) were within the range of physiological values. There was statistical significance compared with before training (P<0.05). There was no significant difference in urine red blood cell count during training. After transient increase to (138.11±14.07) g/L, myoglobin recovered to nearly normal level [(25.20±11.12) g/L], and the 1 km running performance of recruits was (226.2±19.3) s, which was significantly higher than that before the new training, and the difference was statistically significant (P<0.05).Conclusions The intensive recruit training program does not cause damage to kidney, and as a more sensitive indicator, urinary microprotein can effectively indicate the early renal function impairment after training.
Key words
military training /
renal function impairment /
urine microprotein /
serum creatinine /
urinalysis
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References
[1] 向 桢,安运锋,张和君,等.部队官兵军事训练诱发早期肾损伤风险调查研究[J].解放军医药杂志,2020,32(4):107-110.
[2] 吴广礼,黄旭东.军事训练相关性急性肾损伤[J].解放军医学杂志,2019,44(7):555-560.
[3] 曲 辉,钱 瑞,王 闯.国外马拉松运动损伤研究的前沿与进展--基于科学知识图谱的可视化分析[J].辽宁体育科技,2018,24(6):55-61.
[4] 吴广礼,王丽晖,张丽霞,等. 5 km 武装越野跑致肾损伤34例[J]. 人民军医,2004,47(9):515-517.
[5] 周中源,史媛媛,王 梦,等. 有氧运动抑制NLRP3炎性小体活化减轻2型糖尿病小鼠肾脏损伤[J]. 中国运动医学杂志,2021,40(12):962-969.
[6] 衣雪洁,常 波,许豪文. 力竭性游泳运动对大鼠肾脏线粒体功能损伤的影响[J]. 体育科学,2001,21(6):59-61.
[7] Jonatan B C,Sophie G, Frederic J. Mineralocorticoid receptor antagonists and kidney diseases: pathophysiological basis[J]. Kidney Int,2019,96(2):302-319.
[8] Liu Q,Zhang Y,Mao H,et al.A Cr osstalk between the smad and JNK signaling in the TGF-β-induced epithelial-mesenchymal transition in rat peritoneal mesothelial cells [J].PLOS One,2012,7(2):e32009.
[9] 李剑荣,袁 维,杨秋红,等.军事训练伤发病危险因素的Meta分析[J].中国疗养医学,2023,32(4):10.
[10] 陈 洪,张宝和,张朝阳,等. 肾损伤分子-1、中性粒细胞明胶酶相关脂质运载蛋白在早期诊断高强度军训致肾损伤的临床研究[J]. 中国急救复苏与灾害医学杂志,2014,9(11):1016-1020.
[11] 王 舒. 剧烈运动致横纹肌溶解引发急性肾损伤[J]. 临床医药文献电子杂志,2017,4(39):7712.
[12] 魏 霞,袁慧欣,司 钊.武警某部新兵肾脏功能指标评价[J].临床检验杂志(电子版),2019,8(2):60-61
[13] Jeffrey S F, David B, Ahmed I,et al.Effect of age and acute-moderate intensity exercise on biomarkers of renal health and filtration [J]. Biology (Basel), 2022 Mar 30 (4):527.
[14] 姬景章,李忠信,王秀芬,等. 尿微量白蛋白测定的生物学变异研究[J]. 天津医科大学学报,2000,6(2):138-141.
[15] Ionas P, Artemissia P N. Assessing performance in pre-season wrestling athletes using biomarkers[J]. Biochem Med (Zagreb),2018,28(2):20706.
[16] 牛衍龙,曹建民,周海涛,等. 6周大强度训练对大鼠肾功能的影响及其机制[J]. 中国应用生理学杂志,2018,34(1):65-68.
[17] 李 猛,周春华. 剧烈运动引起的肾损伤[J]. 北京医学,2008,30(10):616-618.
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