Objective To study the prognosis of pars plana vitrectomy (PPV)for open globe injury and explore the relevant factors. Methods The clinical data of 241 patients (241 eyes) with open globe injury who received PPV treatment in Department of Ophthalmology of Sichuan Provincial Corps Hospital of Chinese People’s Armed Police Force, Leshan Ophthalmic Center and Ophthalmic Hospital Affiliated to Chengdu University of Traditional Chinese Medicine from January 2013 to December 2022 were retrospectively studied. Preoperative clinical features were recorded, including gender, age, type of injury, zone of trauma, intraocular foreign bodies, visual acuity, intraocular pressure, relative afferent pupillary defect, time between trauma and pars plana vitrectomy, infectious endophthalmitis, and tissue involvement. Individualized surgery was performed based on each patient’s condition and followed up for 6 months after surgery. Visual acuity, intraocular pressure, refractive media, retinal reattachment, and eyeball retention and removal were recorded at each follow-up. According to the final follow-up results, the surgical prognosis was evaluated. Multivariate regression analysis was used to investigate the correlation between preoperative clinical features and surgical prognosis. Results In 241 eyes, 113 eyes (46.9%) had anatomical cure, 93 eyes (38.6%) had functional cure, 206 eyes (85.5%) were cured altogether, 35 eyes (14.5%) were not cured, and 17 eyes (7.1%) underwent enucleation. Multivariate regression analysis showed that the total cure rate was correlated with the type of injury, the area of injury, and the time between injury and operation, and the enucleation rate was correlated with the type of injury, preoperative visual acuity, and the time from injury to operation. Conclusions PPV is effective in the treatment of open globe injury. The type of injury, area of injury, preoperative visual acuity, and time between injury to pars plana vitrectomy are the related factors that affect the surgical prognosis.
Key words
open globe injury /
pars plana vitrectomy /
prognosis /
multifactor analysis /
risk factor /
surgical timing
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