Correlation analysis between smoking and glomerular hyperfiltration in male recruits

ZHANG Chun; AN Lianqing; CHEN Junhua; LIU Zhenjiang; WANG Lixiang; LI Haiyang; CAI Guangyan

PDF(967 KB)

Medical Journal of the Chinese People Armed Police Forces ›› 2024, Vol. 35 ›› Issue (8) : 645-649.

Correlation analysis between smoking and glomerular hyperfiltration in male recruits

ZHANG Chun¹, AN Lianqing², CHEN Junhua³, LIU Zhenjiang⁴, WANG Lixiang⁵, LI Haiyang⁵, CAI Guangyan⁶

Author information +

History +

Abstract

Objective To analyze the correlation between smoking and glomerular hyperfiltration in male recruits. Methods A cross-sectional study was conducted on 1898 male recruits in a military unit in 2023, who were classified according to different smoking status and different estimated glomerular filtration rate, and the influence on estimated glomerular filtration rate was evaluated by binary logistic regression analysis. Results Univariate analysis showed that the estimated glomerular filtration rate was statistically significant with smoking, smoking index, body mass index, systolic blood pressure, diastolic blood pressure, heart rate, red blood cell count, and serum creatinine (P<0.05). Multivariate logistic regression analysis showed that smoking was independently associated with glomerular hyperfiltration compared with non-smokers (OR=2.029, 95%CI: 1.104-3.731), the probability of glomerular hyperfiltration was more than 2 times. Compared with mild smoking index, heavy smoking index was associated with glomerular hyperfiltration (OR=2.497, 95%CI: 1.010-6.175). Conclusions Smoking is an influencing factor in estimating glomerular filtration rate in male recruits and is independently associated with glomerular hyperfiltration.

Key words

smoking / recruits / estimated glomerular filtration rate / glomerular hyperfiltration

Cite this article

EndNote

Ris (Procite)

Bibtex

Download Citations

ZHANG Chun, AN Lianqing, CHEN Junhua, LIU Zhenjiang, WANG Lixiang, LI Haiyang, CAI Guangyan. Correlation analysis between smoking and glomerular hyperfiltration in male recruits[J]. Medical Journal of the Chinese People Armed Police Forces. 2024, 35(8): 645-649

References

[1] Orth S R. Cigarette smoking: an important renal risk factor-far beyond carcinogenesis[J]. Tob Induc Dis, 2002,1(2):137-155.
[2] Dupuis M E, Nadeau-Fredette A C, Madore F, et al. Association of glomerular hyperfiltration and cardiovascular risk in middle-aged healthy individuals[J]. JAMA Netw Open,2020,3(4): e202377.
[3] Moriya T, Tanaka S, Sone H, et al. Patients with type 2 diabetes having higher glomerular filtration rate showed rapid renal function decline followed by impaired glomerular filtration rate: Japan diabetes complications study[J]. J Diabetes Complications, 2017,31(2):473-478.
[4] Oh S W, Yang J H, Kim M G, et al. Renal hyperfiltration as a risk factor for chronic kidney disease: A health checkup cohort study[J]. PLoS One,2020,15(9): e0238177.
[5] Adela H, Harris R. Lieberman, Tracey J. Smith. Department of Defense health related behaviors survey of active duty military personnel[J]. BMC Public Health, 2018(18): 853-854.
[6] Chen F X, Hu P W,Chang W, et al. A Cross-sectional survey on cigarette smoking in the Chinese navy[J]. Mil Med, 2019,184(5-6): e211-e217.
[7] World Health Organization International Tobacco Control Policy Evaluation Project[EB/OL]. Available at http://www.itcproject.org/surveys,accessed June 4, 2018.
[8] Maeda I, Hayashi T, Sato K K, et al. Cigarette smoking and the association with glomerular hyperfiltration and proteinuria in healthy middle-aged men[J]. Clin J Am Soc Nephrol, 2011,6(10):2462-2469.
[9] Stefansson K, Andersson J, Sderberg S, et al.Smoking tobacco is associated with renal hyperfiltration[J].Scand J Clin Lab Inv,2021, 81(8):622-628.
[10] Reboldi G, Verdecchia P, Fiorucci G, et al. Glomerular hyperfiltration is a predictor of adverse cardiovascular outcomes[J]. Kidney Int, 2018, 93(1):195-203.
[11] 翟颖超,涂艳,曹冰.高性能歼击机飞行员吸烟现况的调查分析[J].空军医学杂志,2021,6(37): 209-212.
[12] Halimi J M, Giraudeau B, Vol S, et al. Effects of current smoking and smoking discontinuation on renal function and proteinuria in the general population[J]. Kidney Int, 2000,58: 1285-1292.
[13] Yoon H J, Park M, Yoon H, et al. The differential effect of cigarette smoking on glomerular filtration rate and proteinuria in an apparently healthy population[J]. Hypertens Res, 2009,32: 214-219.
[14] Fox C S, Larson M G, Leip E P, et al: Predictors of new-onset kidney disease in a community-based population[J]. JAMA,2004,291: 844-850.
[15] Yamagata K, Ishida K, Sairenchi T, et al. Risk factors for chronic kidney disease in a community-based population: A 10-year follow-up study[J]. Kidney Int,2007,71:159-166.
[16] Cachat F, Combescure C, Cauderay M, et al. A systematic review of glomerular hyperfiltration assessment and definition in the medical literature[J]. CJASN, 2015,10(3):382-389.
[17] Srivastava T, Hariharan S, Alon U S, et al. Hyperfiltration-ediated injury in the remaining kidney of a transplant donor[J]. Transplantation, 2018, 102:1624-1635.
[18] Brenner B M, Lawler E V, Mackenzie H S. The hyperfiltration theory: a paradigm shift in nephrology[J]. Kidney Int, 1996, 49:1774-1777.
[19] Chagnac A, Zingerman B, Rozen-Zvi B, et al. M. Consequences of glomerular hyperfiltration: the role of physical forces in the pathogenesis of chronic kidney disease in diabetes and obesity[J]. Nephron,2019, 143: 38-42.
[20] Hall M E, Wang W, Okhomina V, et al. Cigarette smoking and chronic kidney disease in African Americans in the Jackson heart study[J]. J Am Heart Assoc,2016,(6): e003202.
[21] Lin J, Zhu K G, Paula K,et al. Electronic cigarette use and related factors among active duty service members in the U.S[J]. Mil Med,2020,185(3-4):418-427.