Predictive value of platelet count for acute exacerbation of chronic obstructive pulmonary disease complicated with bronchiectasis

LI Xinglong; ZHAO Jie; LIU Keyuan; YAN Weijia; BAI Yuan; HUANG Qiaoqiao

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Medical Journal of the Chinese People Armed Police Forces ›› 2025, Vol. 36 ›› Issue (10) : 835-840.

Predictive value of platelet count for acute exacerbation of chronic obstructive pulmonary disease complicated with bronchiectasis

LI Xinglong, ZHAO Jie, LIU Keyuan, YAN Weijia, BAI Yuan, HUANG Qiaoqiao

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Abstract

Objective To analyze the clinical features of acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and AECOPD complicated with bronchiectasis (BE) and to explore the value of platelet count in predicting AECOPD combined with BE (AECOPD-BE). Methods A retrospective analysis was conducted to collect the clinical data of AECOPD patients who visited Chongqing Municipal Corps Hospital of Chinese People’s Armed Police Force from 2021 to 2023. The patients with AECOPD were assigned to the control group (AECOPD group), while those with AECOPD-BE were assigned to the case group (AECOPD-BE group). The basic conditions and clinical indicators were compared between the two groups and the influencing factors of AECOPD combined with BE were analyzed. Results A total of 470 AECOPD patients were included and 59 patients (12.55%) had BE. The average platelet count of the AECOPD-BE group 228.00 (182.00, 279.00)]×10⁹/L] was significantly higher than that of the AECOPD group [197.00 (154.00, 237.75)×10⁹/L], and the difference was statistically significant (Z=-3.731, P<0.001). Multivariate logistic regression analysis revealed that elevated platelet count (OR=1.003, 95% CI: 1.001-1.006) was a risk factor for AECOPD-BE, with an area under the curve of 0.651 (P<0.05). Conclusions Elevated platelet count is a risk factor for AECOPD combined with BE, which has certain predictive value in AECOPD-BE patients.

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acute exacerbation of chronic obstructive pulmonary disease / bronchiectasis / comorbidity / platelet count / influencing factors

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LI Xinglong, ZHAO Jie, LIU Keyuan, YAN Weijia, BAI Yuan, HUANG Qiaoqiao. Predictive value of platelet count for acute exacerbation of chronic obstructive pulmonary disease complicated with bronchiectasis[J]. Medical Journal of the Chinese People Armed Police Forces. 2025, 36(10): 835-840

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