Objective To explore the application and evaluation of HFMEA (healthcare failure mode and effect analysis) and decision tree model in the management of multidrug-resistant organism (MDRO) infection in medical institutions. Methods The HFMEA risk assessment method and decision tree analysis were used to screen out high-risk factors of MDRO infections in the Third People’s Hospital of Yancheng City of Jiangsu Province from June 2023 to December 2023. Targeted improvement intervention measures were adopted and rectification was implemented from January to June 2024, with a comparative analysis conducted to assess the effects before and after the interventions. Results Among the 48 failure modes, 7 high-risk modes that need improvement were selected for intervention. By comparing the MDRO management indicators before and after intervention, it was found that the comprehensive target assessment compliance rates of nosocomial infection before and after intervention were 81.6% and 92.1% respectively, with no statistically significant difference. After the intervention, the other 6 indicators: the awareness rate of the MDRO infection risk assessment system in the department, the execution rate of the MDRO risk assessment in the department, the effective isolation rate of MDRO-infected patients, the qualified rate of the training and examination of clinical physicians on antimicrobial drugs, the qualified rate of the review of antimicrobial drug prescriptions, and the deduction rate of the department for not implementing MDRO prevention and control measures were compared with those before the intervention, and the differences were statistically significant (P<0.05). Conclusions HFMEA and decision tree model as management tools are effective in evaluating the risk of MDRO infection in medical institutions, which can optimize the management process of MDRO, promote the improvement of management measures in departments such as medical care, nursing, and pharmacy, and effectively prevent the spread and outbreak of MDRO within hospitals.
Key words
failure mode and effect analysis /
decision tree analysis /
multidrug-resistant organism /
nosocomial infection
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References
[1] Yun L, Yuan C, Wang M, et al. Development and validation of machine learning models to predict MDRO colonization or infection on ICU admission by using electronic health record data[J]. Antimicrob Resist In, 2024, 13(1):74.
[2] 邓 勇, 毛 平, 何艳红, 等.医院获得性感染耐碳青霉烯类肠杆菌科细菌的耐药性及感染者的临床结局[J].武警医学, 2024, 35(7):621-626.
[3] Mutters N T, Günther F, Frank U, et al. Costs and possible benefits of a two-tier infection control management strategy consisting of active screening for multidrug-resistant organisms and tailored control measures(Article)[J].J Hosp Infect, 2016, 93(2): 191-196.
[4] 冯秉华, 司 迎, 祖 静, 等.医院感控成本投入分析与改进措施[J].武警医学, 2019, 30(11):1017-1018.
[5] Medina E, Pieper, Dietmar H. Tackling threats and future problems of multidrug-resistant bacteria[J]. Curr Top Microbiol, 2016, 398:3-33.
[6] Xu Y L, Wang W Z, Li Z M, et al. Effects of healthcare failure mode and effect analysis on the prevention of multi-drug resistant organisms infections in oral and maxillofacial surgery[J]. Am J Transl Res, 2021, 13(4):3674-3681.
[7] 汪 瑶,叶 青.多重耐药菌感染患者医院感染风险评估量表构建[J].中华医院感染学杂志, 2023, 33(22):3486-3490.
[8] Yi L, Chen Y, Hu R, et al. Application of healthcare failure modeand effect analysis in controlling surgical instrument packaging defects[J]. Sci Rep, 2022, 1(1):19708.
[9] 张 敏.医疗失效模式与效应分析在新生儿首针乙型肝炎疫苗、卡介苗接种中的应用[J].护理实践与研究, 2019, 16(10):122-124.
[10] 邬 燕, 陈 婉, 谢永兰, 等.基于HFMEA预防ICU多重耐药菌医院感染暴发的效果评价[J]. 中国感染控制杂志, 2023, 22(1):102-109.
[11] 殷 玲, 王丹熙, 何 露.多学科协作结合 PDCA 循环法在医院感染管理中的应用价值[J].中西医结合护理(中英文), 2024, 10(9):148-150.
[12] 马小菊, 黎婉斌, 何达秋, 等.基于多学科协作的HFMEA对医院感染的控制效果[J].暨南大学学报(自然科学与医学版), 2024, 45(4):420-427.
[13] 万 滢, 吴德芳, 徐 丽, 等.多学科协作联合集束化管理在血液内科耐碳青霉烯类肠杆菌科细菌感染防控中的应用研究[J].全科护理, 2021, 19(25):3532-3535.
[14] 谢彩颜, 黄敏芳, 廖春花,等.多学科协作模式管理在医院多重耐药菌感染防控中的应用效果[J].中西医结合护理(中英文),2021, 7(8):178-180.
[15] 平小娟, 王玉兰, 黄 华, 等.非公立医疗机构多学科协作医院感染管理查房模式的实践[J].上海护理, 2021, 21(6):59-62.
[16] 王月华.多学科协作管理在多重耐药菌医院感染防控中的效果[J].中国医药科学, 2021, 11(5):193-196.
[17] 曾金秋,陈明玉.多学科协作管理在重症医学科多重耐药菌医院感染防控中的效果探讨[J].中国卫生标准管理, 2023, 14(21):162-165.
[18] 刘 杰.多学科协作模式管理在多重耐药菌医院感染中的应用[J].中国医药指南, 2020, 18(3):129-130.
[19] Giardina M, Tomarchio E, Cantone M C, et al. A review of healthcare failure mode and effects analysis (hfmea) in radiotherapy(article)[J]. Health Physics, 2016, 111(4):317-326.
[20] 周燕妮, 陈晓蕾, 皇甫淑娇, 等. HFMEA在急诊外科危重患者院内安全转运管理中的应用[J].护理管理杂志, 2021, (5):375-379.