Objective To explore the clinical efficacy of Er, Cr:YSGG laser combined with concentrated growth factor membrane in the treatment of peri-implantitis. Methods A total of 60 patients with peri-implantitis from the Department of Stomatology of Affiliated Hospital of Weifang Medical College between February 2021 and February 2024 were included in the study and randomly divided into an experimental group (n=30)and a control group (n=30). The control group received GBR surgery + Er,Cr:YSGG laser irradiation + collagen membrane, while the experimental group received GBR surgery+ Er,Cr:YSGG laser irradiation + CGF membrane. The total effective rate, PLI, SBI, PD, CAL, and changes in inflammatory factors IL-1β, IL-6, and MMP-8 in gingival crevicular fluid were compared between the two groups; the aesthetic indicators, implant stability, patient quality of life, and pain conditions of the dental area before and 3 months after treatment were compared between the two groups. Results After three months of treatment, the total effective rate of the experimental group (96.7%) was higher than that of the control group (80.0%) (P=0.04). Compared with baseline measurements, PLI, SBI, PD, CAL, and inflammatory factors in GCF decreased in both groups after treatment, with the experimental group showing a more pronounced reduction (P<0.05). Additionally, the aesthetic indicators, implant stability, quality of life, and pain scores improved in both groups compared to pre-treatment levels, with the experimental group demonstrating significantly greater improvements than the control group (P<0.05). Conclusions Er,Cr:YSGG laser combined with CGF membrane has better clinical efficacy for peri-implantitis, which can reduce inflammation and pain, and improve aesthetic effects.
Key words
Er,Cr:YSGG laser /
concentrated growth factor membrane /
peri-implantitis /
implant stability /
inflammatory factors
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