Clinical efficacy of CO2 laser-assisted triamcinolone acetonide in the treatment of hypertrophic scars

LIU Lingling; LIANG Liwei; WANG Xiaoxue; AN Haiyan; LI Jin; QIU Shulin; LI Xiaodong

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Medical Journal of the Chinese People Armed Police Forces ›› 2025, Vol. 36 ›› Issue (12) : 1035-1039.

Clinical efficacy of CO₂ laser-assisted triamcinolone acetonide in the treatment of hypertrophic scars

LIU Lingling, LIANG Liwei, WANG Xiaoxue, AN Haiyan, LI Jin, QIU Shulin, LI Xiaodong

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Abstract

Objective To explore the clinical efficacy of CO₂ laser-assisted triamcinolone acetonide (TAA) injection for the treatment of hypertrophic scars. Methods A retrospective analysis was performed on 56 patients with hypertrophic scars who received CO₂ laser-assisted injection therapy at the 980th Hospital PLA Joint Logistics Support Force from June 2021 to March 2023. Before the first treatment and 2 months after the last treatment, the effective rate was used to evaluate the treatment effect. The Vancouver Scar Scale (VSS) was used to evaluate the color, vascularity, softness, and thickness of the scar, and the Visual Analogue Scale (VAS) was used to assess the degree of pain and itching. The patient treatment satisfaction of patients and the occurrence of adverse reactions were recorded. Results The average number of treatments was 4.41 times. Two months after the last treatment, the overall effective rate was 98.21%, and the VSS scores (color, vascularity, softness, thickness) and VAS scores (pain, itching) were significantly improved compared with those before treatment (P＜0.001). The subjective satisfaction rate of patients reached 80.36%, and no adverse reactions such as wound infection, blisters, scar aggravation, and pigmentation changes occurred. Conclusions CO₂ laser-assisted TAA injection for the treatment of hypertrophic scars has a definite efficacy, without adverse reactions, which has clinical application value for promotion.

Key words

CO₂ laser / hypertrophic scar / triamcinolone acetonide / infiltration therapy / combined therapy

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LIU Lingling, LIANG Liwei, WANG Xiaoxue, AN Haiyan, LI Jin, QIU Shulin, LI Xiaodong. Clinical efficacy of CO₂ laser-assisted triamcinolone acetonide in the treatment of hypertrophic scars[J]. Medical Journal of the Chinese People Armed Police Forces. 2025, 36(12): 1035-1039

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