Objective To explore the pathological features and incidence patterns of gastric precancerous lesions, and benign and malignant tumors in the stomach region of a certain region of Tianjin. Methods The pathological diagnosis results of 28110 cases of gastroscopy from a tertiary general hospital in Tianjin from July 2014 to August 2024 were extracted. The features of the disease spectrum, as well as the lesion sites, pathological type, differentiation degrees, gender, age, etc. of precancerous lesions and gastric cancer were analyzed. Results The main types of diseases diagnosed by gastroscopy included inflammatory diseases (68.25%), benign tumors and malignant tumors. There were 19186 cases of gastric inflammatory diseases, among which chronic atrophic gastritis accounted for 35.72% (6 854/19 186) and chronic non-atrophic gastritis for 63.46% (12 176/19 186), all of which were more common in the gastric antrum. Among the 7 587 cases of benign tumors, polyps accounted for 93.73% (7 111/7 587). Among the 716 cases of malignant tumors, adenocarcinoma accounted for 72.07% (516/716) and gastrointestinal stromal tumors accounted for 22.77% (163/716). The average age of patients with low and low-to-moderately differentiated adenocarcinoma was 64.00 (56.00, 71.00) years, while that of patients with moderately and moderately-to-highly differentiated adenocarcinoma was 70.04±9.38 years.The age difference between the two groups was statistically significant (P＜0.05). The detection rate of gastric cancer in males was higher than that in females, and the detection rate of low and low-to-moderately differentiated adenocarcinoma was higher than that of moderately and moderately-to-highly differentiated adenocarcinoma before the age of 60. Gastric dysplasia was detected in 3,720 cases, with a detection rate of 13.23% (3,720/28,110). The average age of high-grade dysplasia (HGD) was 63.35±10.31, and that of low-grade dysplasia (LGD) was 59.00 (51.00, 66.00) years. The age difference between the two groups was statistically significant (P＜0.05). Intestinal metaplasia was detected in 9,922 cases, with a detection rate of 35.30% (9,922/28,110), and the average age was 59.00 (51.00, 65.00) years. Conclusions Gastric malignant tumors in the area of Tianjin are mainly adenocarcinoma and stromal tumors. It is recommended that people in this region, especially males (over 40 years old or earlier), should regularly undergo gastroscopy for early detection and intervention to reduce the incidence.
Key words
gastroscope /
pathology /
disease spectrum /
precancerous lesion /
dysplasia /
intestinal metaplasia /
gastric cancer
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