Effects of physical exercise on serum uric acid metabolism and body composition of young adult males with hyperuricemia

BI Ying; LI Yaxin; YANG Jie; SONG Jie; YANG Zhengmao; YAO Min

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Medical Journal of the Chinese People Armed Police Forces ›› 2025, Vol. 36 ›› Issue (9) : 782-786.

ORIGINAL ARTICLES

Effects of physical exercise on serum uric acid metabolism and body composition of young adult males with hyperuricemia

BI Ying¹, LI Yaxin², YANG Jie³, SONG Jie⁴, YANG Zhengmao¹, YAO Min¹

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Abstract

Objective To explore the effects of physical exercise on serum uric acid metabolism and body composition of young adult males with hyperuricemia (HUA). Methods The physical examination data of 48 young adult males with HUA who underwent unified exercise in the spring of 2024 were sorted and analyzed. A retrospective analysis was conducted on monthly follow-up data, including serum uric acid levels, height, weight, waist circumference and hip circumference. Changes in uric acid, body mass index (BMI), and waist-to-hip ratio (WHR) during the 4-month period of physical exercise were compared, and the correlation analysis was performed between uric acid changes and changes in BMI and WHR. Results During the physical exercise period, serum uric acid levels significantly decreased compared to the baseline from the first month. (P＜0.05), with the most pronounced reduction at the 4-month mark. After 4 months, 29.17% of recruits achieved serum uric acid levels below 420 μmol/L, and 93.75% fell below 540 μmol/L. Both BMI and WHR showed significant reductions (P＜0.05). The reduction in uric acid levels was positively correlated with the decrease in WHR beginning at 2 months of exercise (P＜0.05), and began to be positively correlated with the decrease in BMI at 3 months of exercise (P＜0.05). Conclusions Physical exercise significantly improves serum uric acid levels, BMI, and WHR in young adult males with HUA, with a positive correlation observed between uric acid reduction and decreases in both BMI and WHR. Combining physical exercise with body fat and weight management can provide an effective health management strategy for the reduction of uric acid levels in young adult males with HUA.

Key words

hyperuricemia / physical exercise / body mass index / waist-to-hip ratio;young adult males

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BI Ying, LI Yaxin, YANG Jie, SONG Jie, YANG Zhengmao, YAO Min. Effects of physical exercise on serum uric acid metabolism and body composition of young adult males with hyperuricemia[J]. Medical Journal of the Chinese People Armed Police Forces. 2025, 36(9): 782-786

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