Value of ultrasound elastography in the diagnosis of papillary thyroid carcinoma and its correlation with clinical pathological features

WU Xiaowei; QIAN Wei; CHEN Xulan

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Medical Journal of the Chinese People Armed Police Forces ›› 2026, Vol. 37 ›› Issue (2) : 117-122.

Value of ultrasound elastography in the diagnosis of papillary thyroid carcinoma and its correlation with clinical pathological features

WU Xiaowei, QIAN Wei, CHEN Xulan

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Abstract

Objective To explore the value of ultrasound elastography in the diagnosis of papillary thyroid carcinoma (PTC) and its correlation with clinical pathological features. Methods A retrospective analysis was conducted on the clinical data of 120 patients with PTC and 120 patients with benign thyroid nodules admitted to Characteristics Medical Center of Chinese People's Armed Police Force between June 2020 and June 2025. The strain ratio (SR) and ultrasound elastography score (ES) of all study subjects were recorded. Receiver operating characteristic curve (ROC) was used to evaluate the diagnostic value of SR and ES for PTC, and the correlation between SR, ES and the clinical and pathological features of PTC patients was analyzed. Results The differences in SR, ES and microvascular density (MVD) between the study group and the control group were statistically significant (P＜0.05). The ROC curve results showed that the AUC values for the diagnostic accuracy of PTC using ultrasound elasticity imaging parameters SR, ES, and their combined use were 0.844 (95%CI:0.777~0.911), 0.841 (95%CI:0.761~0.921), and 0.903 (95%CI:0.844~0.961), respectively. There were statistically significant differences in SR and ES among PTC patients with different TNM stages, capsular invasion, number of lesions, differentiation grade, extra-glandular invasion, lateral neck lymph node metastasis, and central zone lymph node metastasis (P＜0.05). Conclusions Ultrasound elastography has high diagnostic value for PTC. The SR and ES parameters of ultrasound elastography are closely related to the clinical pathological features of PTC patients. Analysis of related parameters can help determine the severity of PTC invasion.

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papillary thyroid carcinoma / ultrasound elastography / strain rate ratio / ultrasound elastography score / pathological features

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WU Xiaowei, QIAN Wei, CHEN Xulan. Value of ultrasound elastography in the diagnosis of papillary thyroid carcinoma and its correlation with clinical pathological features[J]. Medical Journal of the Chinese People Armed Police Forces. 2026, 37(2): 117-122

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