目的 探讨慢性心力衰竭(chronic heart failure,CHF)患者心功能和血尿酸(uric acid,UA)水平及左室重构程度的关系。

Objective To evaluate the association of the serum uric acid (UA) level with cardiar function in chronic heart failure(CHF)patients． Methods A total of 236 CHF patients were divided into three groups according to the New York Heart Association (NYHA) criteria．The number of NYHA II-IV was 78，86，72 respectively．According to levels of serum UA, the patients were divided into two groups: normal UA group(132) and hyperuricemia group(104).All the patients underwent the routine test during the emergency disposal or the next morning after admission. They received echocardiography one week after admission．LVEDd，LVPWd，and LVEF were measured． Result CHF patients had a high level of UA. The incidence of hyperuricemia was 44.1%, correlated with the NYHA grades（χ2=8．46，P<0.05).The level of serum UA was also correlated with the NYHA grades (F=11．68，P<0.05)．The level of LVEDd was higher in patients of hyperuricemia than in normal UA. Simple linear correlation confirmed that LVEDd (r=0.386,P<0.01) and LVEF (r=-0.324,P<0.05) are correlated with UA． Conclusion Serum UA is correlated with the NYHA grades in CHF patients．