目的 探讨晕痣与白癜风的相关性及祛除晕痣中央痣对疗效的影响。方法 收集2010-07至2017-10就诊于武警特色医学中心白癜风门诊的晕痣患者的临床资料进行统计学分析。结果 144例晕痣患者平均发病年龄(20.69±12.73)岁,皮损单发118例(81.94%),多发26例(18.06%),好发于躯干部(48.62%)及面颈部(41.44%)。125例合并白癜风,其中非节段型占108例(86.40%),节段型占17例(13.60%),与单纯晕痣患者相比就诊时病程较长(P=0.014)。随访106例合并白癜风患者的临床转归情况,祛除晕痣中央痣的疗效明显好于非手术治疗组(P=0.001),而采取CO2激光或者手术祛除晕痣中央痣两种方式之间差异无统计学意义(P=0.694)。17例单纯晕痣患者祛除晕痣中央痣组总体有效率为91.67%,明显好于非手术治疗组。结论 晕痣好发于青少年,皮损以单发多见,以躯干、面颈部好发。大部分晕痣合并白癜风,且以非节段型为主。祛除晕痣中央痣对于晕痣本身及伴发白癜风均可加快其消退。
Abstract
Objective To study the correlations between halo nevi and vitiligo and to explore the curative effect of eliminating the central nevus of a halo nevus.Methods The clinical data on patients with halo nevi treated in the Department of Dermatology of our hospital between July 2010 and October 2017 was collected and analyzed statistically.Results The average age of 144 cases of halo nevi was (20.69±12.73)years, among whom there were 118 cases of single skin lesions (81.94%) and 26 cases (18.06%) of multiple skin lesions. The halo nevi occurred in the trunk (48.62%) and face and neck. (41.44%). Among the 125 patients with vitiligo, 108 (86.40%) were non-segmental and 17 (13.60%) were segmental, and the duration of the disease was longer when compared with patients with simple halo nevi (P=0.014). The clinical outcomes of 106 patients with vitiligo were followed up. The curative effect of eliminating the central nevus of halo nevi was better than that of the non operative treatment group (P=0.001), but there was no statistically significant difference between the two methods of CO2 laser or surgical of central nevus of halo nevus(P=0.694). The overall effective rate was 91.67% in 17 patients with halo nevi who had the central nevus eliminated, which was significantly better than that of the non operative treatment group.Conclusions Halo nevus with a single lesion is frequently seen in adolescents, which occurs more frequently in the trunk and face and neck. Most of the halo nevi associated with vitiligo are non-segmental. The elimination of the central nevus can accelerate the regression of halo nevi and vitiligo.
关键词
晕痣 /
白癜风 /
临床特点 /
相关性 /
疗效
Key words
halo nevus /
vitiligo /
clinical features /
clinical relevancy /
clinical curative effect
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基金
天津市科技计划项目(14JCYBJC29200)
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