类固醇激素与自体骨髓注射结合弹性髓内针治疗儿童长骨单纯性骨囊肿的临床对照研究

杜英杰; 姚佳岐; 刘丽; 邓湘玲; 李文超

doi:10.3969/j.issn.1004-3594.2026.06.006

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武警医学 ›› 2026, Vol. 37 ›› Issue (6) : 491-496. DOI: 10.3969/j.issn.1004-3594.2026.06.006

论著

类固醇激素与自体骨髓注射结合弹性髓内针治疗儿童长骨单纯性骨囊肿的临床对照研究

杜英杰¹, 姚佳岐¹, 刘丽², 邓湘玲², 李文超²

作者信息 +

Comparative Clinical Study of Corticosteroid versus Autologous Bone Marrow Injection Combined with Elastic Stable Intramedullary Nailing for Pediatric Long-Bone Unicameral Bone Cyst

DU Yingjie¹, YAO Jiaqi¹, LIU Li², DENG Xiangling², LI Wenchao²

Author information +

文章历史 +

摘要

目的比较弹性髓内针(ESIN)分别联合类固醇激素与自体骨髓(ABM)注射治疗儿童长骨单纯性骨囊肿(UBC)的疗效与安全性。方法回顾性分析2015-01至2023-12解放军总医院第一医学中心和第七医学中心收治的UBC患儿45例,分为A组(21例,ESIN+类固醇激素)和B组(24例,ESIN+ABM)。术后定期行影像学随访,依据Capanna标准评估囊肿愈合情况。结果 45例均获随访,平均随访40.4个月。A组总有效率为90.5%(19/21),B组总有效率为91.7%(22/24),两组差异无统计学意义(P=0.89)。45例中,治愈28例(62.2%),部分愈合13例(28.9%),复发2例(4.4%),治疗无效2例(4.4%)。结论 ESIN分别联合类固醇激素与ABM注射均是治疗UBC安全有效的微创方法。

Abstract

Objective To compare the efficacy and safety of elastic stable intramedullary nailing (ESIN) combined with corticosteroid versus combined with autologous bone marrow (ABM) injection in the treatment of unicameral bone cyst (UBC) in the long bones of children. Methods A retrospective analysis was performed on 45 children with UBC admitted to the First and the Seventh Medical Centers of the PLA General Hospital from January 2015 to December 2023. The patients were divided into group A (n=21, ESIN plus corticosteroid) and group B (n=24, ESIN plus ABM injection). Postoperative imaging follow-up was performed regularly, and cyst healing was evaluated according to the Capanna criteria. Results All the 45 patients completed follow-up, with a mean follow-up duration of 40.4 months. The overall effective rate was 90.5% (19/21) in group A and 91.7% (22/24) in group B, with no statistically significant difference between the two groups (P=0.89). Among the 45 cases, 28 (62.2%) achieved complete healing, 13(28.9%) had partial healing, 2(4.4%) developed recurrence, and 2(4.4%) showed no response to treatment. Conclusions Both ESIN combined with corticosteroid and ESIN combined with ABM injection are safe and effective minimally invasive methods for the treatment of UBC.

导出引用

杜英杰, 姚佳岐, 刘丽, 邓湘玲, 李文超. 类固醇激素与自体骨髓注射结合弹性髓内针治疗儿童长骨单纯性骨囊肿的临床对照研究[J]. 武警医学. 2026, 37(6): 491-496 https://doi.org/10.3969/j.issn.1004-3594.2026.06.006

DU Yingjie, YAO Jiaqi, LIU Li, DENG Xiangling, LI Wenchao. Comparative Clinical Study of Corticosteroid versus Autologous Bone Marrow Injection Combined with Elastic Stable Intramedullary Nailing for Pediatric Long-Bone Unicameral Bone Cyst[J]. Medical Journal of the Chinese People Armed Police Forces. 2026, 37(6): 491-496 https://doi.org/10.3969/j.issn.1004-3594.2026.06.006

中图分类号： R726.8

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