目的 探讨超声二维斑点追踪成像技术（speckle tracking imaging,STI）对继发性甲状旁腺功能亢进（pathogenesis of secondary hyper-parathyroidism,SHPT）患者左室心肌收缩功能的评价作用。方法 入选90例慢性肾功能不全患者及30例健康人（对照组）作为研究对象，慢性肾功能不全患者分成伴发有继发性甲状旁腺功能亢进60例（病例组）和甲状旁腺功能正常30例（观察组），三组应用GE Vivid 7 Dimension超声心动图仪获得高帧频二维图像，使用GE Echo PAC软件测量左室短轴3个水平（二尖瓣水平、乳头肌水平及心尖水平）18个室壁节段的收缩期峰值径向应变（SR）和周向应变（CS）。结果 在对照组同一水平比较，观察组短轴径向应变差异无统计学意义；与对照组相比，病例组与观察组部分节段心肌收缩期SR值和CS值差异有统计学意义（P<0.05），其中病例组更为明显。结论 STI能够定位和定量的评价SHPT患者左室不同节段心肌的收缩功能。

Objective To evaluate the left ventricular myocardial function using ultrasonic two-dimensional speckles tracing imaging technology(STI) in patients with secondary hyperparathyroidism(SHPT). Methods Thirty healthy volumteers(control group) and ninety patients with chronic renal failure（CRF） were enrolled in the study. Ninety patients with CRF were divided into 2 groups: 60 patients with SHPT (trial group),30 patients with normal PTH(observed group). The two-dimensional images were obtained from GE Vivid 7 Dimension echocardiograph and two-dimensional radial strain(SR) and circumferential strain(CS) were analyzed on GE Echo PAC system.Left ventricular peak SR and CS values of basel plane,papillary muscle plane and apical plane during systole were measured. Results In the same level,the CS values of anteroseptal segment were higher than those of the other segments in the control group.Compared with the control group,the ventricular peak SR and CS values in part of segments were lower in trial group (P<0.05). Conclusions Left ventricular overall myocardial function in patients with SHPT can be evaluated accurately by STI.