目的 分析消化内科患者经外周静脉中心静脉置管（peripherally inserted central catheter, PICC）导管感染并发症的相关因素，为PICC导管的护理及并发症的预防提供参考。方法 收集142例消化内科行PICC患者的临床资料，记录性别、年龄、原发疾病、PICC穿刺方法、穿刺部位、导管护理频率、穿刺血管、是否合并心血管疾病及糖尿病等资料，采用单因素分析PICC导管感染并发症发生的相关因素，采用Logistic回归分析PICC导管感染的影响因素。结果 导管相关感染并发症发生率为18.3%，其中是否合并心血管疾病、穿刺部位、穿刺方法及护理频率是PICC导管相关感染并发症发生的相关因素；合并心血管疾病、低护理频率是PICC导管相关感染并发症发生的危险因素，肘上部位穿刺是保护性因素。结论 PICC导管感染并发症多与穿刺部位、护理频率及内科合并症有关，要采取针对性的护理措施，降低PICC导管相关感染并发症的发生。

Objective To analyze the related factors of infective complication in patients with digestive diseases carrying peripherally inserted central catheter (PICC) and provide reference for nursing and prevention of complication in PICC. Methods Clinical data of 142 patinets with digestive diseases on PICC were enrolled,and sex,age,primary diseases, puncturing methods, puncturing site,nursing frequency of catheter, punctured blood vessel，presence of or no complicated angiocardiopathy and diabetes mellitus were recorded, related factors of infective complication in PICC were analyzed by single factor method,influencing factors of infective complication in PICC were analyzed by Logistic regression method. Results Infective complication incidence rate was 18.3%，puncturing methods, puncturing site,nursing frequency of catheter and presence or no complicated angiocardiopathy were related factors of infective complication in PICC; complicated angiocardiopathy and lower nursing frequency were risk factors of infective complication in PICC,and puncturing site of higher elbow joint was protective factor of infective complication in PICC. Conclusions Infective complication in PICC is correlative with puncturing position,nursing frequency and medical complication. Directed nursing intervention should be taken to decrease infective complication in PICC.