目的 观察应用紫蓝方加味口服和外洗联合阿维A胶囊及卡介菌多糖核酸注射液治疗扁平疣的效果。 方法 将108例扁 平疣患者随机分2组，治疗组56例，予以口服和外用紫蓝方，同时联合阿维A胶囊及卡介菌多糖核酸注射液治疗；对照组52例 ，仅予以紫蓝方内服和外洗。4周后进行疗效评定和对比。 结果 治疗组痊愈率89.29%，总有效率96.43%，对 照组痊愈率和总有效率分别为69.23%,82.69%。二者比较差异均有统计学意义( χ 2=6.69, P <0.05； χ 2=5.56, P <0.05)。 结论 紫蓝方加味内服和外洗联合阿维A胶囊及卡介菌多糖核酸注射液治疗扁 平疣疗效确切。

Objective To study the clinical efficacy of Zilan Decoction combined with acitretin and BCG-polysaccharide nucleic acid in the treatment of verruca plana. Methods One hundred and eight patients with verruca plana were randomly divided into two groups：the treatment group (56 patients)and the control group (52 patients). Zilan Decoction combined with acitretin and BCG-polysaccharide nucleic acid were given to the treatment group while the control group was treated with Zilan Decoction alone．Four weeks later，the therapeutic efficacy was analyzed after completion of the therapy. Results The curative rate was 89.29% in the treatment group and 69.23% in the control group. The total effective rate was 96.43% in the treatment group and 82.69% in the control group. There was statistically significant difference in the curative rate and total effective rate between the two groups. The results of statistics for the two groups were χ 2=6.69, P <0.05 and χ 2=5.56, P <0.05, separately. Conclusions Zilan Decoction combined with acitretin and BCG-polysaccharide nucleic acid phototherapy is more effective than Zilan Decoction alone in the treatment of verruca plana.