目的 探讨老年患者脂肪性肝病(fatty liver disease，FLD)的特点及其与血尿酸水平等代谢指标的相关性。方法 选择住院患者268例，年龄69～88(78.5±10.2)岁，分为非脂肪肝组和脂肪肝组。分析其脂肪肝的特点及与血尿酸水平等代谢指标的相关性。结果 老年患者以非酒精性轻中度脂肪肝为主要特点，脂肪肝组的血尿酸、谷丙转氨酶、血糖、体质量指数、低密度脂蛋白胆固醇、三酰甘油均高于非脂肪肝组;血红蛋白低于非脂肪肝组;脂肪肝组冠心病、糖尿病、脑卒中的发病率高;差异均有统计学意义(均P<0.05)。Logistic回归分析显示，冠心病、脑卒中、吸烟、GPT高、尿酸高、血红蛋白低是脂肪肝的危险因素，均呈正相关(均P<0.05)。其他指标未进入方程。结论 老年患者以非酒精性轻中度脂肪肝为主要特点，脂肪肝患者的尿酸、血脂、体质量指数高，冠心病、糖尿病、脑卒中的发病率高，血红蛋白低。对老年患者除控制冠心病的常见危险因素外，还应重视脂肪肝、高尿酸血症、低血红蛋白的综合治疗。

Objective To observe the features and association between non alcoholic fatty liver and serum uric acid (UA) and other metabolic dysfuntions in senile patients. Methods A total of 268 patients, with an average age of (78.5?10.2)years, were divided into two groups: fatty liver (FLD) group and non fatty liver group. The association of UA and other metabolic dysfuntions between the two groups was analyzed. Results The levels of UA with FLD(408.32?65.43)mmol/L were significantly higher in fatty liver group than those non fatty liver group(329.79?87.99)mmol/L. (P<0.05). Levels of coronary heart disease with FLD(66.2%)was significantly higher than those in non fatty liver group(39.1%)(P<0.05). Patients with FLD had higher body mass index (BMI), higher glutamate-pyruvate transaminase (GPT), higher blood glucose, higher triglyeride han patients with non fatty liver (all P<0.05), lower hemoglobin than patients with non fatty liver (P<0.05). Logistic regression with FLD as the dependent variables showed that coronary heart disease was positively correlated with FLD, smoking, high UA, GPT and low hemoglobin (all P<0.05). Conclusions Coronary heart disease is closely associated with FLD. Patients with FLD is correlated positively to UA, diabetes mellitus, high triglyeride and coronary heart disease and low hemoglobin.