目的 观察适当的康复训练量对多发性硬化症(multiple sclerosis，MS)患者运动功能状态和复发率的影响。方法 将140例MS后3个月以内的患者随机分为观察组 105例(按康复训练强度分为低、中、高运动量组各35例)和对照组35例。所有MS患者均接受常规的康复护理和药物治疗;观察组同时给予40 min/次，2次/d的康复功能训练，训练时间均为12周。在治疗后进行疗效判定，且分别在治疗前及治疗12周时进行Kurtzke功能障碍状态评定、功能独立性评定(FIM)量表积分和复发率的比较。结果 治疗12周后，(1)观察组在疗效、运动功能积分状态、复发率等方面都明显优于对照组;(2)观察组内三组比较:中运动量组治疗后在疗效、运动功能状态、复发率方面都明显优于低、高运动量组。结论 适量的康复训练对改善MS患者运动功能状态和降低复发率有显著效果。

Objective To observe the effects of appropriate amount of rehabilitation training exercise on functional status and relapse rate in patients with multiple sclerosis. Methods 140 pationts with multiple sclerosis within three months were randomly divided into observation group (105 cases, further divided into subgroups of low rehabilitation training intensity exercise, medium exercise therapy group, and hihg exercise therapy 35 each) and a control group of 35 cases. All patients with multiple sclerosis underwent conventional rehabilitation care and drug treatment in the observation group (low, medium and high exercise groups) at the same time given 40 min/2 times/d of rehabilitation functional training, for a conrse of 12 weeks. Before treatment and at 12 weeks of treatment, Kurtzke functional barrier state was assessed. The Functional Independence Measure (FIM) scale score and relapse rate after treatment were compared to determine efficacy. Results After 12 weeks of treatment, ① In the observation group (low, medium and high exercise group) in any subgroup, the state of the motor function and the relapse rate were significantly better than those in the control group. ② In subgroups of observation group: the efficacy of motor function in the exercise group after treatment and the relapse rate were significantly better than those in the low and high exercise groups. Conclusion Appropriate amount of rehabilitation training has a significant effect on the functional status in patients with multiple sclerosis and reduces the relapse rate.