纳米混悬剂的制备、表征及其应用研究进展

陈充抒,梁艳,梁莉综述,陈虹审校

武警医学 ›› 2013, Vol. 24 ›› Issue (4) : 358-361.

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武警医学 ›› 2013, Vol. 24 ›› Issue (4) : 358-361.
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纳米混悬剂的制备、表征及其应用研究进展

  • 陈充抒1,梁艳1,梁莉2综述,陈虹3审校
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摘要

在药物研制中发现,近40%的药物是水难溶性的,一些药物甚至难溶于有机溶剂,导致其生物利用度低不能使充分发挥疗效[1],使一些药物在研制开发过程中面临溶解度低、药物稳定性低,口服吸收差等问题,将会直接导致药物生物利用度低。而常规制剂技术难以解决难溶性药物溶解度的问题,严重阻碍高效制剂产品的研发。目前,发现纳米混悬技术给这些难溶性药物提供了重现自身价值的机会。现对纳米混悬剂制备方法、表征及其应用的研究进展做一综述。

关键词

纳米混悬剂 / 难溶性药物 / 制备方法 / 表征 / 应用

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陈充抒,梁艳,梁莉综述,陈虹审校. 纳米混悬剂的制备、表征及其应用研究进展[J]. 武警医学. 2013, 24(4): 358-361
中图分类号: R945   

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