目的评价SysmexXE-2100血细胞分析仪检测外周血标本,出现有核红细胞(nucleatedredbloodcell,NRBC)报警的阳性预期值、阴性预期值以及提示信息Q-flag值在一定区间内的特异性、敏感性。方法选择103例SysmexXE-2100出现NRBC报警(100≤Q-flag值≤300)的标本,以及未出现报警(Q-flag值<100)的标本105例,用手工推片,瑞氏染色显微镜镜检作为金标准复检。结果NRBC提示信息在(100≤Q-flag值≤200)区间的阳性预期值为48%,在(200<Q-flag值≤300)区间的阳性预期值为81%,在(Q-flag值≥100)区间的阳性预期值为60%,在(Q-flag值<100)区间的阴性预期值为86%。结论SysmexXE-2100血细胞分析仪NRBC报警具有较高的敏感性和特异性,但存在一定的干扰因素,报警的阳性预期值与Q-flag值所处区间有关。
Abstract
Objective Toevaluate nucleated red blood cell screening using the Sysmex XE-2100 blood cell analyzer. To analyze positive expected value and negative expected value about the alarm of nucleated red blood cells. And to evaluate the sensitivity and specificity of Q-flag result in a certain range. Methods With manual microscopic examination as the gold standard to recheck 103 cases of Sysmex XE-2100 NRBC alarm (100≤Q-flag≤300) samples and 105 cases of no alarm (Q-flag<100) samples. Results When 100≤Q-flag≤200, the positive expected value was 48%. When 200<Q-flag≤300, the positive expected value was 81%. When Q-flag≥100, the positive expected value was 60%. When Q-flag<100, the negative expected value was 86%. Conclusions Sysmex XE-2100 blood cell analyzer NRBC alarm has high sensitivity and specificity, but there are some interfering factors. The positive expected value of the alarm is associated with the interval about Q-flag value.
关键词
外周血 /
有核红细胞 /
血细胞分析仪 /
显微镜镜检
Key words
peripheral blood /
nucleated red blood cells /
blood cell analyzer /
microscopic examination
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