目的探讨昆明山海棠联合1%吡美莫司软膏治疗面部激素依赖性皮炎的临床疗效。方法72例随机分为2组。治疗组36例，口服昆明山海棠2片/次，3次/d，口服依巴斯汀10mg/次，1次/d，外用吡美莫司软膏2次/d。对照组36例，口服依巴斯汀10mg/次，1次/d，外用本院制剂润肤霜软膏2次/d，疗程均为4周。结果治疗组有效率(67%)，显著高于对照组(17%)，且无明显不良反应。结论昆明山海棠联合吡美莫司软膏治疗面部激素依赖性皮炎的疗效明显，安全性好，值得推广。

Objective To observe the therapeutic effect of Tripterygium hypoglaucum Hutch combined with Pimecrolimus in treating patients with facial corticosteroid addiction dermatitis. Methods Seveny-two patients with facial corticosteroid addicted dermatitis were randomly dividecl into the study group (n=36) and the control group (n=36). The subjects in study group were given Tripterygium hypoglaucum Hutch two tabltes orally one time,three times a day and ebastine 10 mg orally one time, a day and topocal pimecrolimus ointment two time a day. The subjects in control group were given ebastine 10 mg orally,one time a day and topical cream made in this hospital, two times a day. The therapeutie effects and adverse effects weve observed after treatment for two and four weeks. Results In the study group,36 cases could be evoluated at the end with a efficacy rate of 67%. In the control group , 36 cases finished the clinical trial with a efficacy rate of 17%.There was a statistically significant difference between the two groups. Conclusions Trpterypium hypoglaucum Hutch combined with pimecrolimus is effective and safe in treating facial corticosteroid addicted dermatitis and deserves to be used wildely.