目的 探讨多种膳食纤维配伍改善功能性便秘的效果。方法 对30例功能性便秘患者采用自身对照试验方法, 每天早晚冲服10 g多种膳食纤维组成的固体饮料, 连续15 d。通过观察患者排便困难程度、粪便性状、排便不尽感、排便频率、腹胀改善情况和生活质量量表评分, 了解膳食纤维改善便秘的效果。结果 服用8 d后, 排便频率、粪便性状、排便不尽感、排便困难差异有统计学意义。服用15 d后, 显效者占90%, 有效率达96.67%, 但随访1个月后, 有效率下降为16.67%。结论 多种膳食纤维配伍的固体饮料改善功能性便秘作用确切, 服用方便, 依从性良好。

Objective To study the effect of combined different dietary fibers on patients with functional constipation. Methods Thirty patients with functional constipation were recruited and given oral administration of combined of different dietary fibers for 15 d. The symptoms of constipation and fecal condition were observed and quantified using scores. Quality of Life (PAC-QOL) scale was used to assess the quality of life in patients with functional constipation before and after treatment. Results After 8 d oral administration of dietary fiber, constipation, fecal condition, poor defecation and defecation frequency were significantly different. After 15 d oral administration, the excellence rate was 90％ and the effective rate was 96.67％. But after follow-up for 1 month, the effective rate decreased to 16.67％. Conclusions The combination of different dietary fibers is an effective therapy for functional constipation.