[1] Deedwania P C. Metabolic syndrome and vascular disease: is nature or nurture leading the new epidemic of cardiovascular disease?[J]. Circulation, 2003, 109(1): 2-4. [2] Bonora E. The metabolic syndrome and cardiovascular disease [J]. Ann Med, 2006, 38(1): 64-80. [3] Aggarwal. Metabolic syndrome and coronary artery disease in indians younger than 40 years[J]. J Endocrinol Metab, 2012: 536-538. [4] Timóteo A T, Mota Carmo M, Cruz Ferreira R. Does metabolic syndrome predict significant angiographic coronary artery disease? [J].Revista Portuguesa De Cardiologia,2012,31(12): 769-778. [5] Malik S. Impact of the metabolic syndrome on mortality from coronary heart disease, cardiovascular disease, and all causes in United States adults[J]. Circulation,2004,110(10): 1245-1250. [6] Ginsberg H N. Insulin resistance and cardiovascular disease[J]. J Clin Invest, 2000,106(4): 453-458. [7] Koning L, Malik V S, Kellogg M D,et al. Sweetened beverage consumption, incident coronary heart disease, and biomarkers of risk in men[J]. Circulation, 2012,125(14): 1735-1741. [8] Wu Q, Zhao Z. Inhibition of PAI-1: a new anti-thrombotic approach[J]. Curr Drug Targets Cardiovasc Haematol Disord, 2002,2(1): 27-42. [9] Austin M A, King M C, Vranizan K M, et al. Atherogenic lipoprotein phenotype: a proposed genetic marker for coronary heart disease risk[J]. Circulation,1990, 82(2): 495-506. [10] Pirro M, Mauriège P, Tchernof A, et al. Plasma free fatty acid levels and the risk of ischemic heart disease in men: prospective results from the quebec cardiovascular study[J]. Atherosclerosis ,2002,160(2): 377-384. [11] 刘 毅, 李宏光, 蔡元菊, 等. 高糖高脂饮食对新西兰兔肝功能的影响[J]. 现代预防医学,2011,38(7): 1237-1239. [12] Pischon T, Boeing H, Hoffmann K. General and abdominal adiposity and risk of death in europe[J]. J Vasc Surg,2008,49(3): 811-812. [13] Poirier P. Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss: an update of the 1997 American Heart Association scientific statement on obesity and heart disease from the obesity committee of the council on nutrition, physical activity, and metabolism[J]. Circulation,2006,113(6): 898-918. [14] Hiro T, Hirayama A, Ueda Y,et al. Rationale and design of a randomized clinical study to investigate the effect of ezetimibe, a cholesterol absorption inhibitor, on the regression of intracoronary plaque evaluated by non-obstructive angioscopy and ultrasound: the zipangu study[J]. J Cardiol,2014,2:105-107. [15] Lavie C J, Milani R V, Ventura H O. obesity and cardiovascular disease[J]. Jac, 2009,53(21): 1925-1932. [16] Poirier P. Obesity and cardiovascular disease: pathophysiology, evaluation, and effect of weight loss [J]. Arterioscler Thromb Vasc Biol, 2006,26(5):968-976. [17] Cooper-DeHoff R M, Gong Y, Handberg E M, et al. Tight blood pressure control and cardiovascular outcomes among hypertensive patients with diabetes and coronary artery disease[J]. Jama,2010,304(1): 61-68. [18] Sipahi I, Tuzcu E M, Schoenhagen P, et al. Effects of normal, pre-hypertensive, and hypertensive blood pressure levels on progression of coronary atherosclerosis[J]. J Ame Colle Card,2006,48(4): 833-838. [19] Slavin T P, Feng T, Schnell A, et al. Two-marker association tests yield new disease associations for coronary artery disease and hypertension[J]. Hum Genet, 2011,130(6): 725-733. [20] TICFBPG-WA. Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk[J]. Nature, 2012,478(7367): 103-109. [21] 孙宇光, 刘辉霞. 高血压/血脂异常及肥胖对围绝经期妇女冠心病的影响[J]. 医学综述,2011,17(18): 2853-2855. [22] Denardo S J, Gong Y, Nichols W W, et al. Blood pressure and outcomes in very old hypertensive coronary artery disease patients: an INVEST substudy[J]. AJM, 2010,123(8): 719-726. [23] Koziróg M, Poliwczak A R, Duchnowicz P, et al. Melatonin treatment improves blood pressure, lipid profile, and parameters of oxidative stress in patients with metabolic syndrome[J]. J Pineal Res,2010,50(3): 261-266. [24] Wu Y, Huxley R, Li L,et al. Prevalence, awareness, treatment, and control of hypertension in China: data from the China National Nutrition and health survey 2002[J]. Circulation,2008,118(25): 2679-2686. [25] Ford E S, Giles W H, Dietz W H. Prevalence of the metabolic syndrome among US adults: findings from the third national health and nutrition examination survey[J]. Jama, 2002,287(3): 356-359. [26] 沈 敏,方权明,胡 艳. 氯沙坦联合松龄血脉康治疗高血压合并代谢综合征的疗效研究[J]. 中国全科医学,2012,15(12): 1414-1416.