目的 探讨中国人群中肥胖与胃食管反流病(gastroesophageal reflux disease,GERD)的相关性。方法 检索自建库至2013-12中国生物医学文献数据库、中国全文期刊数据库、中国科技期刊数据库、PubMed上公开发表的有关中国人群肥胖与GERD发生率关系的文献,按照入选标准,共有9篇横断面研究纳入本研究,对其研究内容摘录后应用Stata 12.0软件进行分析。结果 中国肥胖人群比正常体重人群发生GERD的风险增加,比值比(OR)为1.82,95％可信区间(95％CI)为1.27～2.62。结论 根据现有的研究资料分析,中国肥胖人群发生GERD的风险增加,肥胖是中国人群GERD的相关危险因素之一。
Abstract
Objective To evaluate the association between obesity and gastroesophageal reflux disease (GERD) among Chinese population. Methods The literature about the association between obesity and prevalence of GERD among Chinese population were searched in accordance with inclusion and exclusion criteria up till to December 2013 in electronic databases CBM, CNKI, VIP and Pubmed. The data in nine cross－sectional studies selected were analyzed by Stata 12.0 software. Results There was a significant association between increasing body mass and prevalence of GERD with an odds ratio (OR) of 1.82 (95％ confidential intervals: 1.27－2.62). Conclusions Obesity increases the occurrence of GERD among Chinese population. Obesity is one of the risk factors of GERD.
关键词
胃食管反流病 /
肥胖 /
meta分析
Key words
gastroesophageal reflux disease /
obesity /
meta-analysis
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