目的 探讨功能性腭咽成形术治疗阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome,OSAHS)的疗效。方法 采用功能性腭咽成形术治疗多平面阻塞OSAHS患者58例,术后6个月进行睡眠监测系统和CT上气道连续扫描复查,与术前数据比较,判定疗效。结果 全部患者均未出现严重并发症,治愈 3例(5.1%),显效39例(67.2%),有效8例(13.8%),无效8例(13.8%),总有效率 86.2%。手术前后睡眠呼吸暂停低通气指数(apnea hypopnea index,AHI)变化有统计学差异[(65.23±21.27)次/h vs(27.82±18.45)次/h,P<0.05],最低血氧饱和度(SaO₂)有显著变化[(68.35±10.16)% vs(83.73±9.68)%,P<0.05],术后腭后区及舌后区截面积明显扩大(P<0.05)。结论 功能性腭咽成形术是治疗OSAHS安全、有效的方法。

Objective To study the effect of functional PPP on OSAHS. Methods We used micro-movement sensitive mattress sleep monitoring system (MSMSMS) and 256 CT to evaluate the effect of the functional PPP on OSAHS. Results Cure was attained in 3 cases (5.1%),obvious effect in 39 cases(67.2%),effect in 8 cases(13.8%), no effect in 8 cases(13.8%) among 58 patients with OSAHS. AHI(P<0.01) and SaO₂(P<0.05) showed significant difference before surgery and after surgery. The crosssection areas of the posterior areas of palate and tongue were wider than those before surgery .Conclusions Functional UPPP is a safe and efficient treatment for OSAHS.