目的 研究轻度认知功能障碍(mild cognitive impairment, MCI)与老年患者术后的发生谵妄的关系。方法 腰丛联合坐骨神经阻滞下接受髋部骨折手术的认知功能正常老年患者64例和MCI患者45例,ASA Ⅱ～Ⅲ级,在术后1 d、2 d和3 d采用谵妄评定法(confusion assessment method,CAM)评估患者意识、认知、定向、思维、精神运动等方面变化。结果 正常老年组谵妄发生率为12.5%,MCI组谵妄发生率为31.1%,MCI患者的谵妄发生率明显高于正常老年患者。结论 老年MCI患者术后更易发生谵妄。

Objective To study the incidence of postoperative delirium in elderly patients with mild cognitive impairment. Methods From June 2012 to August 2013, we recruited 64 elderly patients with normal cognition and 45 elderly patients with mild cognitive impairment undergoing hip fracture fixation. We tested the patients’ cognition at 1d, 2d and 3d postoperatively according to confusion assessment method (CAM) for diagnosis of postoperative delirium (POD). Results The incidence of POD in normal elderly patients was 12.5%, while the incidence in elderly patients with mild cognitive impairment was 31.1%. Conclusion The elderly patients with mild cognitive impairment have higher incidence of POD.