目的 了解某院抗菌药物不合理应用的整治成效,以及对医院感染控制的影响。方法 调查2011-10至2013-09全院抗菌药物使用率、使用强度和限制级以上药物使用前送检率的变化,以及同期住院患者感染率情况,并行统计学分析。结果 通过两年整治,抗菌药物使用前送检率显著上升,由2.34%升至60.72%,使用率及使用强度显著下降;但同期住院患者感染率并未发生明显变化。结论 抗菌药物不合理应用整治对于控制抗菌药物滥用及促进合理用药具有良好作用,且对医院感染发生率无明显影响。

Objective To investrqate the effects of antibiotics use management on the hospital infection rates at the same time. Methods The changes in antibiotics utilization rates, use requency, specimen examination rates and infection rates of in hospitalized patients, at the same period were investigated. Statistical analysis was done after that. Results It showed marued increase in specimen examination rates significant downward trend in the utilization rate and marked decrease of frequency of antibiotrcs the use, in hospitalized patients in these two years, but the hospital infection rates did not change significantly at the same period. Conclusions Antimicrobial treatment has a good role in controlling the costs of medicines and promoting the rational drug use, but will not affect the anti-infection treatment and control clinically.