目的 观察地佐辛联合罗哌卡因用于臂丛神经阻滞的麻醉效果。方法 选择40例需行上肢手术的患者,随机分为A,B两组(每组20例)。各组均在超声引导下行臂丛神经阻滞,局麻药为0.5%罗哌卡因30 ml。A组不加地佐辛;B组局麻药中加入地佐辛10 mg。记录各组患者的麻醉起效时间、痛觉消失时间及镇痛持续时间。同时采用VAS评分评价患者麻醉后4、6、8 h的镇痛效果,并观察各组患者的不良反应。结果 B组的镇痛持续时间明显长于A组[(12.03±3.07) h vs (9.28±2.16) h,P<0.05)]。麻醉后8 h B组的VAS评分显著低于A组[(3.97±1.42) vs (6.38±2.32),P<0.05)],且无明显不良反应。结论 地佐辛联合罗哌卡因应用于臂丛神经阻滞能显著延长麻醉镇痛时间,且无明显不良反应。
Abstract
Objective To observe the effects of dezocine combined with ropivacaine in brachial plexus block. Methods Forty patients who were subjected to upper limb surgery were randomly divided into groups A and B (n=20 for each group ). The brachial plexus block was performed under ultrasound guiding with 0.5% ropivacaine 30 ml. In group A, no dezocine was added. Local anesthetic in group B consisted of dezocine 10 mg. Onset time of anesthesia,pain free time, duration of analgesia, postanethesia visual analogue scale(VAS) at 4, 6, 8 h and side effects were recorded. Results The duration of analgesia in group B was significantly longer than that in group A [(12.03?3.07) h vs (9.28?2.16) h, P<0.05)]. Postanesthesia VAS score at 8 h in group B was significantly lower than that in group A [(3.97?1.42) vs (6.38?2.32), P<0.05)]. There was no significant difference between group A and B about the incidence of side effects. Conclusion Dezocine combined with ropivacaine in brachial plexus block prolongs the analgesia with fewer side effects.
关键词
地佐辛 /
罗哌卡因 /
臂丛神经阻滞
Key words
dezocine /
ropivacaine /
brachial plexus block
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参考文献
[1] 徐建国,罗爱伦,吴新民,等. 地佐辛术后镇痛专家建议[J]. 临床麻醉学杂志, 2013, 29(9) : 921-922.
[2] 王会敏. 舒芬太尼复合罗哌卡因应用于股神经阻滞效果观察[J]. 中国中医药咨讯, 2011, 3(13) : 377-378.
[3] 周斌福,许南燕,钱敬畏. 罗哌卡因复合地佐辛在臂丛神经阻滞中的应用[J]. 中国中西医结合外科杂志, 2012, 18(2) : 185-187.
[4] 盛卓人,王俊科. 实用临床麻醉学[M]. 4版. 北京:科学出版社,2009:782.
[5] Murphy D B,Mccartney C J,Chan V W.Novel analgesic adjuncts for brachial plexus block a systematic review[J].Anesth Analg,2000,90(5):1122-1128.
[6] Karakaya D,Buyukgoz F,Baris S,et al. Addition of fentanyl to bupivacaine prolongs anesthesia and analgesia in axillary brachial plexus block[J].Reg Anesth,2001,26(5): 434-434.
[7] 祁富军, 任鹏程, 张旭东,等. 地佐辛复合左旋布比卡因应用于臂丛神经阻滞的临床研究[J]. 中华全科医学, 2013, 11(1):23-25.
[8] 林 毅,王松清. 不同剂量地佐辛复合左旋布比卡因术后硬膜外自控镇痛的临床研究[J]. 海峡药学,2012, 24(1):132-133.
[9] 陈 曦. 地佐辛复合罗哌卡因用于腰丛联合坐骨神经阻滞的临床观察[J]. 中国中医骨伤科杂志, 2012, 20(12): 53-54.
[10] Nishikawa K. Fentanyl improves analgesic but prolongs the onset of axillary brachial plexus block by peripheral mechanism[J]. Anesth Analg, 2000, 91(2):384-387.
[11] 师小甜, 熊源长, 刘佩蓉. 地佐辛临床镇痛的研究进展[J]. 医学综述, 2013, 19(6) : 1105-1107.
[12] 杨彦军,朱平增,韩雪萍,等. 结肠癌根治术后地佐辛与舒芬太尼静脉自控镇痛效果比较[J]. 武警医学,2012, 23(4) : 287-289.
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