目的 探讨乳头溢液颜色及溢液量与乳管内相应病变之间的关系。方法 对2014-05至2014-12于武警总医院门诊行乳管镜检查并行相应治疗的174例乳头溢液患者的临床资料进行回顾性分析。结果 174例乳头溢液患者有乳管内占位性病变者共83例(47.7%),其中乳腺癌5例;乳管内无占位性病变者91例(52.3%)。单侧溢液、单孔溢液分别较双侧溢液、多孔溢液在乳管镜下发现乳管内占位的可能性大(P<0.05),血性溢液、淡黄色溢液较其他颜色溢液在乳管镜下发现乳管内占位的可能性大(P<0.05),血性溢液较非血性溢液提示乳腺癌可能性大(P<0.05),单侧溢液中单孔溢液和多孔溢液两者乳管内占位发生率比较无统计学差异。结论 乳头溢液是乳管内病变的早期表现,其中单侧溢液、单孔溢液、血性溢液、淡黄色溢液均提示乳管内占位性病变可能性大,单纯血性溢液是乳腺癌高危因素,单侧溢液无论单孔还是多孔都有临床意义。

Objective To investigate the relationship between the color and volume of nipple discharge and intraductal lesions. Methods The clinical data of 174 patients with nipple discharge who underwent fiberoptic ductoscopy (FDS) in this institution from May 2014 through Dec 2014 were analyzed retrospectively. Results Of the 174 patients, 83 had intraductal space occupying lesions, including 5 cases of breast cancer, and 91 cases without intraductal space occupying lesions. Compared with bilateral, porous nipple discharge, unilateral, uniforate,bloody and intraductal yellow nipple discharge were of much more clinical significance(P<0.05). Compared with non-bloody nipple discharge, bloody nipple discharge had much more possibility of breast cancer(P<0.05). There was no significant difference between uniforate discharge and porous discharge among the patients with unilateral discharge. Conclusion Nipple discharge is an early manifestation of breast intraductal lesions. Unilateral, single hole, bloody and intraductal yellow nipple discharge means much more possibility of intraductal lesion. Bloody nipple discharge is a risk factor of breast cancer. Uniforate discharge and porous discharge among the patients with unilateral discharge is of similar clinical significance.